doripenem

Suppliers

Names

[ Name ]:
doripenem

[Synonym ]:
doripenem
S 4661
InterMediates of DoripeneM
(4R,5S,6S)-6-[(1R)-1-Hydroxyethyl]-4-methyl-7-oxo-3-({(3S,5S)-5-[(sulfamoylamino)methyl]-3-pyrrolidinyl}sulfanyl)-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[(3S,5S)-5-[[(aminosulfonyl)amino]methyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-, (4R,5S,6S)-

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
694.8±65.0 °C at 760 mmHg

[ Melting Point ]:
>186ºC dec.

[ Molecular Formula ]:
C₁₅H₂₄N₄O₆S₂

[ Molecular Weight ]:
420.504

[ Flash Point ]:
374.0±34.3 °C

[ Exact Mass ]:
420.113739

[ PSA ]:
195.74000

[ LogP ]:
-3.65

[ Vapour Pressure ]:
0.0±4.9 mmHg at 25°C

[ Index of Refraction ]:
1.681

[ Storage condition ]:
-20°C Freezer

Safety Information

[ Hazard Codes ]:
N

Precursor & DownStream

Precursor

Doripenem condensation compound
(F-9 (M-6))
4-nitrobenzyl (4R,5R,6S)-6-[(1R)-1-hydroxyethyl]-4-methyl-3,7-dioxo-1-azabicyclo[3.2.0]-heptane-2-carboxylate
L-Hydroxyproline
Boc-Hyp-OH
1-Pyrrolidinecarboxylic acid, 4-(acetylthio)-2-(hydroxymethyl)-, 1,1-dimethylethyl ester, (2S,4S)
(2S,4R)-N-tetr-butoxycarbonyl-4-methanesulfonyloxy-2-hydroxymethylpyrrolidine

DownStream

Related Compounds

DoripeneM Crude
DoripeneM Crude
Doripenem side-chain
DoripenemCondensationCompound
4,7-seco-DoripeneM DisodiuM Salt (Mixture of double bond isoMers)
8-Methyl-1,4-dioxa-spiro[4,5]decane-8-carbaldehyde
2-(Difluoromethyl)butanedioic acid
7-(Benzyloxy)-4-bromo-6-methoxycinnoline
N-(2-morpholinopyrimidin-5-yl)-4-phenylbutanamide
Methyl 5-oxo-4-propanoylheptanoate
2-chloro-4-fluoro-N-(2-morpholinopyrimidin-5-yl)benzamide
N-(3-cyanothiolan-3-yl)-3-methyl-[1,2]oxazolo[5,4-b]pyridine-5-carboxamide
N-[(4-tert-butylphenyl)(cyano)methyl]-5-(dimethylamino)pentanamide
1-[Benzyl(prop-2-yn-1-yl)amino]propan-2-ol
4-(2-Aminoethyl)-3-hydroxybenzoic acid