doripenem

Suppliers

Names

[ Name ]:
doripenem

[Synonym ]:
doripenem
S 4661
InterMediates of DoripeneM
(4R,5S,6S)-6-[(1R)-1-Hydroxyethyl]-4-methyl-7-oxo-3-({(3S,5S)-5-[(sulfamoylamino)methyl]-3-pyrrolidinyl}sulfanyl)-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[(3S,5S)-5-[[(aminosulfonyl)amino]methyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-, (4R,5S,6S)-

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
694.8±65.0 °C at 760 mmHg

[ Melting Point ]:
>186ºC dec.

[ Molecular Formula ]:
C₁₅H₂₄N₄O₆S₂

[ Molecular Weight ]:
420.504

[ Flash Point ]:
374.0±34.3 °C

[ Exact Mass ]:
420.113739

[ PSA ]:
195.74000

[ LogP ]:
-3.65

[ Vapour Pressure ]:
0.0±4.9 mmHg at 25°C

[ Index of Refraction ]:
1.681

[ Storage condition ]:
-20°C Freezer

Safety Information

[ Hazard Codes ]:
N

Precursor & DownStream

Precursor

Doripenem condensation compound
(F-9 (M-6))
4-nitrobenzyl (4R,5R,6S)-6-[(1R)-1-hydroxyethyl]-4-methyl-3,7-dioxo-1-azabicyclo[3.2.0]-heptane-2-carboxylate
L-Hydroxyproline
Boc-Hyp-OH
1-Pyrrolidinecarboxylic acid, 4-(acetylthio)-2-(hydroxymethyl)-, 1,1-dimethylethyl ester, (2S,4S)
(2S,4R)-N-tetr-butoxycarbonyl-4-methanesulfonyloxy-2-hydroxymethylpyrrolidine

DownStream

Related Compounds

DoripeneM Crude
DoripeneM Crude
Doripenem side-chain
DoripenemCondensationCompound
4,7-seco-DoripeneM DisodiuM Salt (Mixture of double bond isoMers)
(2S,3R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-methoxybutanethioic S-acid
Benzyl (S)-(2-((1-amino-1-oxo-3-phenylpropan-2-yl)(benzoyloxy)amino)-2-oxoethyl)carbamate
1-[4-(1H-pyrazol-4-yl)piperidin-1-yl]prop-2-en-1-one
(R)-(1-Benzyl-6,6-dimethylpiperidin-2-YL)methanol
(R)-1-Benzyl-6-(hydroxymethyl)piperidin-2-one
(3S,5R)-5-methoxypiperidin-3-ol
(5R)-5-amino-1,3-oxazinan-2-one hydrochloride
5-(Perfluoroethyl)-3-(trifluoromethyl)pyridin-2-OL
3-amino-1-benzyl-5-bromo-4-methylpyridin-2(1H)-one
3-Fluoro-5-(propan-2-yl)aniline hydrochloride