chlorphoxim

Names

[ Name ]:
chlorphoxim

[Synonym ]:
EINECS 238-888-9
CHLORPHOXIM
7-(2-chlorophenyl)-4-ethoxy-3,5-dioxa-6-aza-4-phosphaoct-6-ene-8-nitrile 4-sulfide
O,O-diethyl 2-chloro-α-cyanobenzylideneaminooxyphosphonothioate
(1Z)-2-chloro-N-diethoxyphosphinothioyloxybenzenecarboximidoyl cyanide
Chlorphoxin
MFCD00078643
SRA 7747
(EZ)-2-(2-chlorophenyl)-2-(diethoxyphosphinothioyloxyimino)acetonitrile
Chlorphoxime
O,O-diethyl ({[(Ξ)-(2-chlorophenyl)cyanomethylidene]amino}oxy)phosphonothioate

Chemical & Physical Properties

[ Density]:
1.3 g/cm3

[ Boiling Point ]:
391.5ºC at 760 mmHg

[ Molecular Formula ]:
C₁₂H₁₄ClN₂O₃PS

[ Molecular Weight ]:
332.74300

[ Flash Point ]:
190.6ºC

[ Exact Mass ]:
332.01500

[ PSA ]:
105.74000

[ LogP ]:
4.53238

[ Vapour Pressure ]:
2.45E-06mmHg at 25°C

[ Index of Refraction ]:
1.563

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AL8285000

CHEMICAL NAME :: Acetonitrile, 2-(2-chlorophenyl)-2-(diethoxyphosphinothioyloxyimino )-

CAS REGISTRY NUMBER :: 14816-20-7

LAST UPDATED :: 199109

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C12-H14-Cl-N2-O3-P-S

MOLECULAR WEIGHT :: 332.76

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C73,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 8,176,1987

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H311

[ Precautionary Statements ]:
P280-P302 + P352 + P312

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R21

[ Safety Phrases ]:
S22-S25

[ RIDADR ]:
UN 3464 6.1 / PGIII

[ RTECS ]:
AL8285000

Articles

Resistance to organophosphate and carbamate insecticides in Anopheles atroparvus.

Parassitologia 25(1) , 1-8, (1983)

Adult Anopheles atroparvus, from Cadiz, Spain (strain AT SPA) were resistant to several organophosphorus and carbamate insecticides. Separate lines of the AT SPA strain selected with propoxur, fenitro...

Evaluation of chlorphoxim used against Anopheles albimanus on the south coast of Mexico: 1. Results of indoor chlorphoxim applications and assessment of the methodology employed.

Bull. Pan Am. Health Organ. 18(4) , 379-88, (1984)

[Effect of temephos on acetylcholinesterase activity in the brain of Tilapia guineensis. 3: Comparative effect of temephos and 3 substitute insecticides].

Toxicol. Eur. Res. 5(2) , 63-9, (1983)

The Onchocerciasis Control Programme (OCP) is realized in the major part of the treated area by weekly applications of temephos in biotopes of simulles larvae. This insecticide is very effective and i...