3-Amino-L-alanine hydrochloride

Suppliers

Names

[ Name ]:
3-Amino-L-alanine hydrochloride

[Synonym ]:
Propionic acid, 2,3-diamino-, hydrochloride
UNII:IU6ICR549L
L-(+)-2,3-Diaminopropionic acid hydrochloride
MFCD00065497
ALANINE, 3-AMINO-, MONOHYDROCHLORIDE
H-Dap-OH.HCl
3-Aminoalanine hydrochloride (1:1)
(S)-(+)-2,3-Diaminopropionic Acid Hydrochloride
Alanine, 3-amino-, hydrochloride (1:1)
L(+)-2,3-Diaminopropionic acid hydrochloride
H-Dapa-OH·HCl
(S)-2,3-Diaminopropanoic acid hydrochloride
L-2,3-Amino-L-Alanine HCl
3-Amino-L-alanine hydrochloride

Chemical & Physical Properties

[ Boiling Point ]:
329.9ºC at 760mmHg

[ Melting Point ]:
231-233 °C (dec.)

[ Molecular Formula ]:
C₃H₉ClN₂O₂

[ Molecular Weight ]:
140.57

[ Flash Point ]:
153.3ºC

[ Exact Mass ]:
140.035248

[ PSA ]:
89.34000

[ LogP ]:
0.55960

[ Index of Refraction ]:
24 ° (C=2, 1mol/L HCl)

[ Storage condition ]:
2~8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922499990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

(2S)-3-amino-2-[(tert-butoxycarbonyl)amino]propionamide hydrochloride
Cbz-beta-Amino-L-alanine
L-Aspartic acid
(1'S,4S)-1-(1'-Phenyleth-1'-yl)-4-methoxycarbonylimidazolidin-2-one
Boc-D-Dap-OH
tert-butyl (S)-(1,3-diamino-1-oxopropan-2-yl)carbamate
Boc-Dap-OtBu
(-)-2,3-bisacetamidopropanoic acid methyl ester
L-Alanine, 3-(acetylamino)-, methyl ester (9CI)

DownStream

(2S)-2-amino-3-(phenylmethoxycarbonylamino)propanoic acid
Cbz-beta-Amino-L-alanine
(S)-tert-butyl3-amino-2-(((benzyloxy)carbonyl)amino)propanoate
tert-butyl 3-N-carbobenzoxy-(S)-2,3-diaminopropionate
L-Albizziin
2,3-bis[(2,2,2-trifluoroacetyl)amino]propanoic acid
(2S)-3-amino-2-(oxaloamino)propanoic acid

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles

Discovery of Dap-3 polymyxin analogues for the treatment of multidrug-resistant Gram-negative nosocomial infections.

J. Med. Chem. 56(12) , 5079-93, (2013)

We report novel polymyxin analogues with improved antibacterial in vitro potency against polymyxin resistant recent clinical isolates of Acinetobacter baumannii and Pseudomonas aeruginosa . In additio...

Capreomycin — A polypeptide antitubercular antibiotic with unusual binding properties toward copper(II)

J. Inorg. Biochem. 106(1) , 111-6, (2012)

Capreomycin is an important therapeutic agent having intriguing and diverse molecular features. Its polypeptidic structure rich in nitrogen donors makes the drug a promising chelating agent for a numb...

Synthesis of 9-membered dilactams derived from 1,3-diaminopropionic and glutamic acids.

J. Pept. Res. 63(3) , 235-40, (2004)

Previously unknown 9-membered bridged dipeptides derived from l or d isomers of 1,3-diaminopropionic acids and l-glutamic acid were synthesized using aminoacyl incorporation reaction. Key intermediate...