Thioperamide (maleate)

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Names

[ CAS No. ]:
148440-81-7

[ Name ]:
Thioperamide (maleate)

[Synonym ]:
MR-12842 N-Cyclohexyl-4-(1H-imidazol-4-yl)-1-piperidinecarbothioamide maleate salt
1-Piperidinecarbothioamide, N-cyclohexyl-4-(1H-imidazol-5-yl)-, (2Z)-2-butenedioate (1:1)
MR-12842 (N-Cyclohexyl-4-(1H-imidazol-4-yl)-1-piperidinecarbothioamide maleate salt
Thioperamide Maleate
N-Cyclohexyl-4-(1H-imidazol-5-yl)-1-piperidinecarbothioamide (2Z)-2-butenedioate (1:1)
1-Piperidinecarbothioamide, N-cyclohexyl-4-(1H-imidazol-4-yl)-, (2Z)-2-butenedioate (1:1)
MFCD00083209
N-Cyclohexyl-4-(1H-imidazol-4-yl)piperidine-1-carbothioamide (2Z)-but-2-enedioate (1:1)

Chemical & Physical Properties

[ Molecular Formula ]:
C19H28N4O4S

[ Molecular Weight ]:
408.515

[ Exact Mass ]:
408.183136

[ PSA ]:
150.64000

[ LogP ]:
2.83690

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

Articles

Highly potent and selective ligands for histamine H3-receptors.

Nature 327 , 117, (1987)

New drugs selective for histamine H3-receptors can be used to establish that these receptors are involved in the feedback control of histamine synthesis and release, and to demonstrate their distribut...

Effects of the histamine H3-agonist (R)-alpha-methylhistamine and the antagonist thioperamide on histamine metabolism in the mouse and rat brain.

J. Neurochem. 52 , 1388, (1989)

To study the feedback control by histamine (HA) H3-receptors on the synthesis and release of HA at nerve endings in the brain, the effects of a potent and selective H3-agonist, (R)-alpha-methylhistami...

Effect of thioperamide, a histamine H3 receptor antagonist, on electrically induced convulsions in mice.

Eur. J. Pharmacol. 234(1) , 129-33, (1993)

The effect of thioperamide, a histamine H3 receptor antagonist, on electrically induced convulsions was studied in mice. Thioperamide significantly and dose dependently decreased the duration of each ...


More Articles

Related Compounds

  • Thioperamide
  • TPN729 maleate
  • Pimethixene maleate
  • HEPZIDINE MALEATE
  • trimebutine maleate
  • AMlodipine Maleate
  • 6-Bromo-3-(4-chlorophenoxy)-4-hydroxyquinolin-2(1H)-one
  • 2-(5-Bromoindol-1-yl)-5-methyl-1,3,4-oxadiazole
  • 2-(Oxolan-3-yloxy)ethane-1-thiol
  • 1H-Pyrrolo[2,3-b]pyridine-4-carboxamidine
  • Ethyl 3-(2,4-difluorophenyl)-2-oxopropanoate
  • (2R)-2-aminopentan-1,5-diol
  • 2-(Hydroxymethyl)pyrimidine-5-carboxylic acid
  • (1R,2R)-2-aminocyclohexane-1-carbonitrile
  • trans-2-Aminocyclohexanecarbonitrile hydrochloride salt
  • 2-(6-chloropyrimidin-4-yl)-1H-indole
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