ipronidazole

Suppliers

Names

[ Name ]:
ipronidazole

[Synonym ]:
2-isopropyl-1-methyl-5-nitro-(1H)-imidazole
1-methyl-5-nitro-2-(propan-2-yl)-1H-imidazole
ipronidazole
Ipronidazol [INN-Spanish]
Ro 07-1554
1H-Imidazole, 1-methyl-2- (1-methylethyl)-5-nitro-
Ipronidazolo [DCIT]
1H-Imidazole, 1-methyl-2-(1-methylethyl)-5-nitro-
1h-imidazole, 1-methyl-2-(1-methylethyl)-5-nitro
2-Isopropyl-1-methyl-5-nitroimidazole
Ipronidazolum [INN-Latin]
2-Isopropyl-1-methyl-5-nitro-1H-imidazole
1-methyl-2-isopropyl-5-nitroimidazole
Ipropran
1-Methyl-2-(1-methylethyl)-5-nitro-1H-imidazole,2-Isopropyl-1-methyl-5-nitroimidazol
Ro 7-1554

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
309.3±15.0 °C at 760 mmHg

[ Melting Point ]:
60°

[ Molecular Formula ]:
C₇H₁₁N₃O₂

[ Molecular Weight ]:
169.181

[ Flash Point ]:
140.9±20.4 °C

[ Exact Mass ]:
169.085129

[ PSA ]:
63.64000

[ LogP ]:
1.18

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.572

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NI6450000

CHEMICAL NAME :: 1H-Imidazole, 2-isopropyl-1-methyl-5-nitro-

CAS REGISTRY NUMBER :: 14885-29-1

BEILSTEIN REFERENCE NO. :: 0744577

LAST UPDATED :: 199612

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C7-H11-N3-O2

MOLECULAR WEIGHT :: 169.21

WISWESSER LINE NOTATION :: T5N CNJ A1 BY1&1 ENW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - turkey

DOSE/DURATION :: 640 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Yeast - Saccharomyces cerevisiae

DOSE/DURATION :: 5 ppm

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 86,243,1981

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933290090

Customs

[ HS Code ]: 2933290090

[ Summary ]:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Simultaneous determination of 15 nitroimidazoles in cosmetics by HPLC coupled with electrospray ionization- tandem mass spectrometry.

J. AOAC Int. 97(6) , 1538-45, (2015)

A sensitive and reliable analytical method based on HPLC/MSIMS has been developed for the simultaneous determination of 15 nitroimidazoles in cosmetics. A diversity of cosmetic samples, including powd...

Development of a monoclonal antibody-based indirect competitive enzyme-linked immunosorbent assay for nitroimidazoles in edible animal tissues and feeds.

J. Pharm. Biomed. Anal. 120 , 84-91, (2016)

The misuse of nitroimidazoles (NDZs) can lead to NDZs residues in edible animal tissues, which would be harmful to consumer health. To quickly monitor NDZs residues in edible animal tissues and feed, ...

[Determination of three nitroimidazole residues in royal jelly by high performance liquid chromatography-tandem mass spectrometry].

Se Pu 24(4) , 331-4, (2006)

A method for analysis of trace metronidazole (MTZ), dimetridazole (DMZ) and ronidazole (RNZ) residues in royal jelly was developed by high performance liquid chromatography-tandem mass spectrometry (H...