2-piperidin-1-ylethyl 4-amino-5-chloro-2-methoxybenzoate

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Names

[ CAS No. ]:
148868-55-7

[ Name ]:
2-piperidin-1-ylethyl 4-amino-5-chloro-2-methoxybenzoate

[Synonym ]:
2-Piperidinoethyl 4-amino-5-chloro-2-methoxybenzoate

Chemical & Physical Properties

[ Density]:
1.223g/cm3

[ Boiling Point ]:
472.7ºC at 760 mmHg

[ Molecular Formula ]:
C15H21ClN2O3

[ Molecular Weight ]:
312.79200

[ Flash Point ]:
239.7ºC

[ Exact Mass ]:
312.12400

[ PSA ]:
64.79000

[ LogP ]:
3.09260

[ Vapour Pressure ]:
4.18E-09mmHg at 25°C

[ Index of Refraction ]:
1.563

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933399090

Synthetic Route

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Precursor & DownStream

Precursor

  • N-Chloroethyl piperidine
  • 4-Amino-5-Chloro-2-Methoxybenzoic Acid
  • Piperidine

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Design and synthesis of specific probes for human 5-HT4 receptor dimerization studies.

J. Med. Chem. 48 , 6220-6228, (2005)

Recently, human 5-HT4 receptors have been demonstrated to form constitutive dimers in living cells. To evaluate the role of dimerization on the 5-HT4 receptor function, we investigated the conception ...

New esters of 4-amino-5-chloro-2-methoxybenzoic acid as potent agonists and antagonists for 5-HT4 receptors.

J. Med. Chem. 40 , 608-621, (1997)

A number of benzoates derived from 4-amino-5-chloro-2-methoxybenzoic acid and substituted 1-piperidineethanol were synthesized and found to be potent 5-HT4 receptor agonists in the electrically-stimul...

Intestinal motor stimulation by the 5-HT4 receptor agonist ML10302: differential involvement of tachykininergic pathways in the canine small bowel and colon.

Neurogastroenterol. Motil. 13 , 543-553, (2001)

5-Hydroxytryptamine (5-HT)4 receptor agonists stimulate gut motility through cholinergic pathways, although there are data suggesting that noncholinergic (tachykininergic) excitatory pathways may also...


More Articles

Related Compounds

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  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
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  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
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