7-O-(Triethylsilyl) Paclitaxel

Suppliers

Names

[ CAS No. ]:
148930-55-6

[ Name ]:
7-O-(Triethylsilyl) Paclitaxel

[Synonym ]:
7-O-(Triethylsilyl)taxol

Chemical & Physical Properties

[ Molecular Formula ]:
C53H65NO14Si

[ Molecular Weight ]:
968.16700

[ Exact Mass ]:
967.41700

[ PSA ]:
213.78000

[ LogP ]:
7.34000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (2α,5β,7β,10β,13α)-4,10-Diacetoxy-13-{[(2R,3S)-3-(benzoylamino)-2-(benzyloxy)-3-phenylpropanoyl]oxy}-1-hydroxy-9-oxo-7-[(triethylsilyl)oxy]-5,20-epoxytax-11-en-2-yl benzoate
  • 4-bromopent-4-en-1-ol
  • 4-bromo-pent-4-enoic acid ethyl ester
  • 2-bromo-5-(triethylsilyloxy)pentene
  • (1R,2S,5R,6S,7S,8S,9S)-2,6-Dibenzyloxy-5-(tert-butyldimethylsiloxy)-7,9-(isopropylidenedioxy)-4,4,8-trimethyl-12-methylenebicyclo[6.4.0]dodecan-3-one

DownStream

  • Paclitaxel

Related Compounds

  • 7-O-(Triethylsilyl) Paclitaxel
  • 2',3'-O,N-[(S)-(p-Methoxybenzylidene)]-7-O-(triethylsilyl)paclitaxel
  • 2'-O-(tert-butyldimethylsilyl)-4-O-deacetyl-2-O-debenzoyl-7-O-(triethylsilyl)paclitaxel
  • 7-O-(Triethylsilyl)-2'-O-tert-butyl(dimethyl)silyl-2-debenzoyl Paclitaxel
  • 7-O-(Triethylsilyl)-2'-O-tert-butyl(dimethyl)silyl 2-Debenzoyl Paclitaxel 2-Pentanoate
  • 7-O-(Triethylsilyl)-10-deacetyl Baccatin III