Oxymetazoline
Suppliers
Names
[ CAS No. ]:
1491-59-4
[ Name ]:
Oxymetazoline
[Synonym ]:
Oximetazolinum
EINECS 216-079-1
Rhinofrenol
3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethyl-6-tert-butylphenol
MFCD00242798
Iliadin
Oxymethazoline
2-(4-t-butyl-2,6-dimethyl-3-hydroxy-benzyl)-2-imidazoline
Sinerol
6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethyl-phenol
Oxylazine
Nezeril
Hazol
Nafrine
Chemical & Physical Properties
[ Density]:
1.08 g/cm3
[ Boiling Point ]:
431.9ºC at 760 mmHg
[ Melting Point ]:
182ºC
[ Molecular Formula ]:
C16H24N2O
[ Molecular Weight ]:
260.37500
[ Flash Point ]:
215ºC
[ Exact Mass ]:
260.18900
[ PSA ]:
44.62000
[ LogP ]:
2.61510
[ Vapour Pressure ]:
4.59E-08mmHg at 25°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SK1050000
- CHEMICAL NAME :
- Phenol, 6-t-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethyl-
- CAS REGISTRY NUMBER :
- 1491-59-4
- BEILSTEIN REFERENCE NO. :
- 0886303
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C16-H24-N2-O
- MOLECULAR WEIGHT :
- 260.42
- WISWESSER LINE NOTATION :
- T5M CN BUTJ B1R CQ B1 F1 DX1&1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 800 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 18,185,1971
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1100 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 18,185,1971
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2700 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 1,74,1967 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 20 mg/kg
- SEX/DURATION :
- female 1-5 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
- REFERENCE :
- CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 11,563,1975
Safety Information
[ RIDADR ]:
UN 3249
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1(a)
[ HS Code ]:
2933290090
Customs
[ HS Code ]: 2933290090
[ Summary ]:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%