(3R,4S)-4-Phenyl-3-[(Triethylsilyl)Oxy]-2-Azetidinone

Names

[ CAS No. ]:
149140-54-5

[ Name ]:
(3R,4S)-4-Phenyl-3-[(Triethylsilyl)Oxy]-2-Azetidinone

[Synonym ]:
4-phenyl-3-triethylsilanyloxy-azetidin-2-one
(3R,4S)-4-Phenyl-3-[(Triethylsilyl)Oxy]-2-Azetidinone
(3R,4S)-3-[(Triethylsilyl)oxy]-4-phenyl-2-azetidinone

Chemical & Physical Properties

[ Density]:
1.04g/cm3

[ Boiling Point ]:
393.216ºC at 760 mmHg

[ Molecular Formula ]:
C15H23NO2Si

[ Molecular Weight ]:
277.43400

[ Flash Point ]:
191.611ºC

[ Exact Mass ]:
277.15000

[ PSA ]:
41.82000

[ LogP ]:
3.52380

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.516

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Chlorotriethylsilane
  • Cis-3-hydroxy-4-phenyl-2-azetidinone
  • Imidazole
  • azetidinone
  • (2R,3S)-methyl 3-azido-3-phenyl-2-((triethylsilyl)oxy)propanoate
  • 2-Azetidinone, 3-(acetyloxy)-4-phenyl-, (3R,4S)-
  • (3R,4S)-1-((S)-1-(4-methoxyphenyl)propyl)-2-oxo-4-phenylazetidin-3-yl acetate
  • (3R,4S)-3-triisopropylsilyloxy-4-phenylazetidin-2-one

DownStream

  • (3R,4S)-tert-Butyl 2-oxo-4-phenyl-3-(triethylsilyloxy)azetidine-1-carboxylate
  • (3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone