(3R,4S)-tert-Butyl 2-oxo-4-phenyl-3-(triethylsilyloxy)azetidine-1-carboxylate

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Names

[ CAS No. ]:
149198-47-0

[ Name ]:
(3R,4S)-tert-Butyl 2-oxo-4-phenyl-3-(triethylsilyloxy)azetidine-1-carboxylate

[Synonym ]:
tert-Butyl (3R,4S)-2-oxo-4-phenyl-3-[(triethylsilyl)oxy]azetidine-1-carboxylate
MFCD08273948
tert-butyl (3R,4S)-2-oxo-4-phenyl-3-triethylsilyloxyazetidine-1-carboxylate
1-Azetidinecarboxylic acid, 2-oxo-4-phenyl-3-[(triethylsilyl)oxy]-, 1,1-dimethylethyl ester, (3R,4S)-
2-Methyl-2-propanyl (3R,4S)-2-oxo-4-phenyl-3-[(triethylsilyl)oxy]-1-azetidinecarboxylate
(3R,4S)-tert-Butyl 2-oxo-4-phenyl-3-(triethylsilyloxy)azetidine-1-carboxylate

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
463.1±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C20H31NO4Si

[ Molecular Weight ]:
377.550

[ Flash Point ]:
233.9±28.7 °C

[ Exact Mass ]:
377.202240

[ PSA ]:
55.84000

[ LogP ]:
4.38

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.517

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Di-tert-butyl dicarbonate
  • (3R,4S)-4-Phenyl-3-[(Triethylsilyl)Oxy]-2-Azetidinone
  • Imidazole
  • tert-Butoxy(chloro)diphenylsilane
  • H-Thr-OMe.HCl
  • Chlorotriethylsilane
  • Cis-3-hydroxy-4-phenyl-2-azetidinone
  • (3R,4S)-3-triisopropylsilyloxy-4-phenylazetidin-2-one

DownStream

  • cabazitaxel

Related Compounds

  • 1-(4-Amino-5-fluoro-quinazolin-7-yl)-3,6,6-trimethyl-1,5,6,7-tetrahydro-indol-4-one
  • N-(1,3-Benzodioxol-5-ylmethyl)-1-(4-chlorophenyl)-5-(4-piperidinyl)-1H-pyrazole-4-carboxamide
  • 2-[(4-Aminophenyl)sulfanyl]benzonitrile
  • 2-(benzo[d][1,3]dioxol-5-yloxy)-N-(2-(3-(4-ethoxyphenyl)-6-oxopyridazin-1(6H)-yl)ethyl)acetamide
  • 3-(5-(3-Nitrophenyl)furan-2-yl)-1-(pyrrolidin-1-yl)propan-1-one
  • 2-(4-benzoylphenoxy)-N-(2-(3-(4-ethoxyphenyl)-6-oxopyridazin-1(6H)-yl)ethyl)acetamide
  • 1-(3-chlorophenyl)-3-(2-(3-(4-ethoxyphenyl)-6-oxopyridazin-1(6H)-yl)ethyl)urea
  • 1-(2,4-Dimethylphenyl)-3-{2-[3-(4-ethoxyphenyl)-6-oxo-1,6-dihydropyridazin-1-yl]ethyl}urea
  • 1-(3-chloro-4-fluorophenyl)-3-(2-(3-(4-ethoxyphenyl)-6-oxopyridazin-1(6H)-yl)ethyl)urea
  • 1-(2-(3-(4-ethoxyphenyl)-6-oxopyridazin-1(6H)-yl)ethyl)-3-(2-methoxy-5-methylphenyl)urea
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