NE 100 hydrochloride

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Names

[ CAS No. ]:
149409-57-4

[ Name ]:
NE 100 hydrochloride

[Synonym ]:
ne 100
NE-100

Chemical & Physical Properties

[ Boiling Point ]:
475.2ºC at 760 mmHg

[ Molecular Formula ]:
C23H34ClNO2

[ Molecular Weight ]:
391.97500

[ Flash Point ]:
137.4ºC

[ Exact Mass ]:
391.22800

[ PSA ]:
21.70000

[ LogP ]:
5.78320

[ Vapour Pressure ]:
3.37E-09mmHg at 25°C

MSDS

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Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

Diverse regulation of IP3 and ryanodine receptors by pentazocine through σ1-receptor in cardiomyocytes.

Am. J. Physiol. Heart Circ. Physiol. 305(8) , H1201-12, (2013)

Although pentazocine binds to σ1-receptor (σ1R) with high affinity, the physiological relevance of its binding remains unclear. We first confirmed that σ1R stimulation with pentazocine rescues contrac...

A sigma-1 receptor antagonist (NE-100) prevents tunicamycin-induced cell death via GRP78 induction in hippocampal cells

Biochem. Biophys. Res. Commun. 434(4) , 904-9, (2013)

Highlights • NE-100 protected neuronal cells against the tunicamycin-induced cell death. • NE-100 attenuated the upregulation of CHOP induced by ER stress. • NE-100 upregulated the expressions of p50A...

Prediction of drug-drug interactions for AUCoral of high clearance drug from in vitro data: utilization of a microtiter plate assay and a dispersion model.

Curr. Drug Metab. 7(2) , 135-46, (2006)

The purpose of this study was to propose a new method to predict in vivo drug-drug interactions (DDIs) for a high clearance drug from in vitro data. As the high clearance drug, NE-100 (N, N-dipropyl-2...


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Related Compounds

  • HA-100 hydrochloride
  • 10-(a-diethylaminopropionyl)-phenothiazi ne hydrochloride (as-139
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  • 4,5,6,7-Tetrahydro-2-methyl-N-(1-methylethyl)-5-benzothiazolemethanami ne hydrochloride
  • N,N-dimethyl-2-[2-[(E)-2-(3-methyloxazol-5-yl)ethenyl]phenoxy]ethanami ne hydrochloride