Pefloxacin mesylate dihydrate

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Names

[ CAS No. ]:
149676-40-4

[ Name ]:
Pefloxacin mesylate dihydrate

[Synonym ]:
MFCD01685696
1-ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid,methanesulfonic acid,dihydrate
EINECS 274-613-9
Pefloxacin mesilate dihydrate
3-Quinolinecarboxylic acid (1-ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo

Chemical & Physical Properties

[ Boiling Point ]:
529.1ºC at 760mmHg

[ Melting Point ]:
271ºC

[ Molecular Formula ]:
C18H28FN3O8S

[ Molecular Weight ]:
465.49400

[ Flash Point ]:
273.8ºC

[ Exact Mass ]:
465.15800

[ PSA ]:
146.99000

[ LogP ]:
2.06960

[ Storage condition ]:
Store at?0-5°C

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22-36

[ Safety Phrases ]:
26

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
VB2002200

Articles

Pefloxacin-induced achilles tendon toxicity in rodents: biochemical changes in proteoglycan synthesis and oxidative damage to collagen.

Antimicrob. Agents Chemother. 44 , 867-872, (2000)

Despite a relatively low incidence of serious side effects, fluoroquinolones and the fluoroquinolone pefloxacin have been reported to occasionally promote tendinopathy that might result in the complic...

Cytotoxicity and uptake of pefloxacin, ciprofloxacin, and ofloxacin in primary cultures of rat hepatocytes.

J. Antimicrob. Chemother. 24 , 355-363, (1989)

The cytotoxicity and the uptake of three 4-quinolones--pefloxacin, ciprofloxacin, and ofloxacin--were investigated in primary cultures of rat hepatocytes. As assessed by intracellular enzyme release i...


More Articles


Related Compounds

  • Pefloxacin mesylate
  • Pefloxacin mesylate
  • pefloxacin N-oxide
  • Pefloxacin
  • Pefloxacin-D5
  • Almonertinib mesylate
  • 2-(1-Hydroxycyclopentyl)bicyclo[2.2.1]heptane-2-carboxylic acid
  • 2-(3-Hydroxypentan-3-yl)bicyclo[2.2.1]heptane-2-carboxylic acid
  • 1-(2-Ethyl-1-hydroxybutan-2-yl)-3,5-dimethylcyclohexan-1-ol
  • 1-(2-Ethyl-1-hydroxybutan-2-yl)-3,3-dimethylcyclopentan-1-ol
  • 3-(2-Ethyl-1-hydroxybutan-2-yl)-5,5-dimethyloxolan-3-ol
  • 1-[3-(Hydroxymethyl)piperidin-3-yl]cyclopentan-1-ol
  • 1-(1-Hydroxy-2-methylpentan-2-yl)-4-methylcyclohexan-1-ol
  • Ethyl 3,3-difluoro-1-(1-hydroxycyclopentyl)cyclobutane-1-carboxylate
  • Ethyl 3,3-difluoro-1-(1-hydroxycyclobutyl)cyclobutane-1-carboxylate
  • Ethyl 3,3-difluoro-1-(3-hydroxyazetidin-3-yl)cyclobutane-1-carboxylate
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