Pefloxacin mesylate dihydrate
Suppliers
Names
[ CAS No. ]:
149676-40-4
[ Name ]:
Pefloxacin mesylate dihydrate
[Synonym ]:
MFCD01685696
1-ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid,methanesulfonic acid,dihydrate
EINECS 274-613-9
Pefloxacin mesilate dihydrate
3-Quinolinecarboxylic acid (1-ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo
Chemical & Physical Properties
[ Boiling Point ]:
529.1ºC at 760mmHg
[ Melting Point ]:
271ºC
[ Molecular Formula ]:
C18H28FN3O8S
[ Molecular Weight ]:
465.49400
[ Flash Point ]:
273.8ºC
[ Exact Mass ]:
465.15800
[ PSA ]:
146.99000
[ LogP ]:
2.06960
[ Storage condition ]:
Store at?0-5°C
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H319
[ Precautionary Statements ]:
P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
22-36
[ Safety Phrases ]:
26
[ RIDADR ]:
NONH for all modes of transport
[ RTECS ]:
VB2002200
Articles
Antimicrob. Agents Chemother. 44 , 867-872, (2000)
Despite a relatively low incidence of serious side effects, fluoroquinolones and the fluoroquinolone pefloxacin have been reported to occasionally promote tendinopathy that might result in the complic...
J. Antimicrob. Chemother. 24 , 355-363, (1989)
The cytotoxicity and the uptake of three 4-quinolones--pefloxacin, ciprofloxacin, and ofloxacin--were investigated in primary cultures of rat hepatocytes. As assessed by intracellular enzyme release i...