3-(Biphenyl-4-yl)-5-(4-tert-butylphenyl)-4-phenyl-4H-1,2,4-triazole

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Names

[ Name ]:
3-(Biphenyl-4-yl)-5-(4-tert-butylphenyl)-4-phenyl-4H-1,2,4-triazole

[Synonym ]:
3-(4-Biphenylyl)-5-[4-(2-methyl-2-propanyl)phenyl]-4-phenyl-4H-1,2,4-triazole
4H-1,2,4-Triazole, 3-[1,1'-biphenyl]-4-yl-5-[4-(1,1-dimethylethyl)phenyl]-4-phenyl-
3-(Biphenyl-4-yl)-5-(4-tert-butylphenyl)-4-phenyl-4H-1,2,4-triazole
3-(4-tert-butylphenyl)-4-phenyl-5-(4-phenylphenyl)-1,2,4-triazole
3-(4-BiPhenyl)-4-Phenyl-5-Tert-butylPhenyl-1,2,4-Triazole

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
611.5±58.0 °C at 760 mmHg

[ Melting Point ]:
231-235 â„ƒ

[ Molecular Formula ]:
C₃₀H₂₇N₃

[ Molecular Weight ]:
429.556

[ Flash Point ]:
323.6±32.3 °C

[ Exact Mass ]:
429.220490

[ PSA ]:
30.71000

[ LogP ]:
9.55

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.615

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22

[ RIDADR ]:
NONH for all modes of transport

Articles

Inhibitory mechanism of FAT4 gene expression in response to actin dynamics during Src-induced carcinogenesis.

PLoS ONE 10(2) , e0118336, (2015)

Oncogenic transformation is characterized by morphological changes resulting from alterations in actin dynamics and adhesive activities. Emerging evidence suggests that the protocadherin FAT4 acts as ...

Molecular profiling and computational network analysis of TAZ-mediated mammary tumorigenesis identifies actionable therapeutic targets.

Oncotarget 5(23) , 12166-76, (2015)

Triple-negative breast cancer (TNBC) accounts for approximately 15-20% of all breast cancer (BC) cases and contributes disproportionately to BC mortality. TAZ, a key transducer of the Hippo pathway, h...

Characterization of TAZ domains important for the induction of breast cancer stem cell properties and tumorigenesis.

Cell Cycle 14(1) , 146-56, (2015)

The Hippo pathway is an evolutionarily conserved regulator of tissue growth and cell fate during development and regeneration. Conversely, deregulation of the Hippo pathway has been reported in severa...

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