Pranlukast hemihydrate

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Names

[ CAS No. ]:
150821-03-7

[ Name ]:
Pranlukast hemihydrate

[Synonym ]:
Benzamide, N-(4-oxo-2-(1H-tetrazol-5-yl)-4H-1-benzopyran-8-yl)-4-(4-phenylbutoxy)-, hydrate (2:1)
UNII-FR702N558K
Benzamide, N-[4-oxo-2-(2H-tetrazol-5-yl)-4H-1-benzopyran-8-yl]-4-(4-phenylbutoxy)-, hydrate (1:1)
bis{N-[4-oxo-2-(1H-tetrazol-5-yl)-4H-chromen-8-yl]-4-[(4-phenylbutyl)oxy]benzamide} hydrate
Pranlukast hydrate (JAN)
Onon (TN)
N-[4-Oxo-2-(2H-tetrazol-5-yl)-4H-chromen-8-yl]-4-(4-phenylbutoxy)benzamide hydrate (1:1)
pranlukast hydrate
8-[4(4-phenylbutoxy)benzoyl]amino-2-(5-tetrazolyl)-4-oxo-4H-1-benzopyran
Pranlukast hemihydrate
Benzamide,N-(4-oxo-2-(1H-tetrazol-5-yl)-4H-1-benzopyran-8-yl)-4-(4-phenylbutoxy)-,hydrate (2:1)

Chemical & Physical Properties

[ Molecular Formula ]:
C27H23N5O4.1/2H2O

[ Molecular Weight ]:
490.51

[ PSA ]:
132.23000

[ LogP ]:
4.63580

[ Storage condition ]:
2-8℃

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335-H413

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ RIDADR ]:
NONH for all modes of transport

Articles

Improving dissolution and oral bioavailability of pranlukast hemihydrate by particle surface modification with surfactants and homogenization.

Drug Des. Devel. Ther. 9 , 3257-66, (2015)

The present study was carried out to develop an oral formulation of pranlukast hemihydrate with improved dissolution and oral bioavailability using a surface-modified microparticle. Based on solubilit...


More Articles


Related Compounds

  • Pranlukast-d5
  • Pranlukast
  • Pranlukast-d4
  • Canagliflozin hemihydrate
  • Timolol hemihydrate
  • Chlorobutanol hemihydrate
  • (1R,2S)-2-{[2-(tert-butylsulfanyl)ethyl]carbamoyl}cyclopropane-1-carboxylic acid
  • Methyl 2-hydroxyhept-3-enoate
  • 2-Hydroxy-3-(2-methyl-1,3-dioxolan-2-yl)cyclohepta-2,4,6-trien-1-one
  • 1-(4-Chlorophenyl)-2-iodoethanol
  • [(4-Phenylbutyl)thio]benzene
  • 8,2'-Dihydroxyflavone
  • 2-Bromo-5-chlorobenzamide
  • (R)-Di-tert-butyl pyrrolidine-1,2-dicarboxylate
  • N-(2-chlorobenzyl)-2-(2-methyl-4-oxo-7-(p-tolyl)thiazolo[4,5-d]pyridazin-5(4H)-yl)acetamide
  • 2-bromo-6-[(2-tetrahydro-2H-pyranyloxy)methyl]pyridine
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