L-allo-Isoleucine
Suppliers
Names
[ CAS No. ]:
1509-34-8
[ Name ]:
L-allo-Isoleucine
[Synonym ]:
Isoleucine, allo-
Alloisoleucine, L-
UNII:05T3WT3PJ1
L-Alloisoleucine
alle
Alloisoleucine
(2S,3R)-2-Amino-3-methylpentanoic acid
Allo-L-isoleucine
L-Isoleucine
l-aIle
(+)-threo-2-Amino-3-methylpentanoic Acid
Allo-isoleucine
(R)-Isoleucine
D-(-)-Isoleucine
L(+)-Alloisoleucine
(2S,3R)-2-Amino-3-methylpentanoic acid,L-Alloisoleucine
a-Ile
L-Isoleucine, allo-
H-D-Ile-OH
L-ALLO-ISOLEUCINE
MFCD00066446
EINECS 216-142-3
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
225.8±23.0 °C at 760 mmHg
[ Melting Point ]:
-285ºC
[ Molecular Formula ]:
C6H13NO2
[ Molecular Weight ]:
131.173
[ Flash Point ]:
90.3±22.6 °C
[ Exact Mass ]:
131.094635
[ PSA ]:
63.32000
[ LogP ]:
0.73
[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C
[ Index of Refraction ]:
1.463
[ Storage condition ]:
Store at RT.
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BA2933000
- CHEMICAL NAME :
- Alloisoleucine, L-
- CAS REGISTRY NUMBER :
- 1509-34-8
- BEILSTEIN REFERENCE NO. :
- 1721791
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C6-H13-N-O2
- MOLECULAR WEIGHT :
- 131.20
- WISWESSER LINE NOTATION :
- QVYZY2&1 -L,ALLO
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 6954 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - body temperature decrease
- REFERENCE :
- ABBIA4 Archives of Biochemistry and Biophysics. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.31- 1951- Volume(issue)/page/year: 58,253,1955
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
26-36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
BA2933000
Precursor & DownStream
Precursor
DownStream
Articles
Pediatr. Res. 25 , 11-14, (1989)
The nonprotein amino acid L-allo-isoleucine is formed endogenously in maple syrup urine disease patients from (R)-3-methyl-2-oxo-pentanoic acid. During strict metabolic balance, the plasma L-allo-isol...
Biochem. Med. Metab. Biol. 41 , 105-116, (1989)
Possible functional differences in the catabolism of the four branched-chain L-amino acids in maple syrup urine disease were assessed using cultured human skin fibroblast stains. Transamination and ox...
Biochem. J. 301 , 367-372, (1994)
Potential substrates for L-delta-(alpha-aminoadipoyl)-L-(cysteinyl)-D-valine (ACV) synthetase were initially identified using both the amino-acid-dependent ATP<-->pyrophosphate exchange reaction catal...