Z2CN

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Names

[ CAS No. ]:
151-18-8

[ Name ]:
Z2CN

[Synonym ]:
3-Amino-1-propanethiolHCl
Propanenitrile, 3-amino-
chlorhydrate de mercapto-3 propylamine
3-amino-propionitrile
3-mercapto-1-propylamino hydrochloride
3-Aminopropionitrile
3-Mercaptopropylamine hydrochloride
EINECS 205-786-0
MFCD00014820
Z2CN
N-(2-Cyanoethyl)amine
beta-aminopropionitrile
2-Cyanoethylamine
3-cyanoethylamine
3-aminopropanonitrile
1-Propanethiol,3-aMino-,hydrochloride
3-Aminopropionitrile Fumarate
3-thiopropylamine hydrochloride
3-Aminopropanenitrile
aminopropylthiol hydrochloride
β-Aminopropionitrile
homocysteamine hydrochloride
3-aminopropanethiol hydrochloride
aminoethylcyanide

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
186.3±13.0 °C at 760 mmHg

[ Molecular Formula ]:
C3H6N2

[ Molecular Weight ]:
70.093

[ Flash Point ]:
66.5±19.8 °C

[ Exact Mass ]:
70.053101

[ PSA ]:
49.81000

[ LogP ]:
-1.02

[ Vapour Pressure ]:
0.7±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.430

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UG0350000
CHEMICAL NAME :
Propionitrile, 3-amino-
CAS REGISTRY NUMBER :
151-18-8
BEILSTEIN REFERENCE NO. :
1698848
LAST UPDATED :
199701
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C3-H6-N2
MOLECULAR WEIGHT :
70.11
WISWESSER LINE NOTATION :
Z2CN

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
12800 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - cyanosis
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1152 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
10 gm/kg/11D-I
TOXIC EFFECTS :
Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
5 gm/kg
SEX/DURATION :
female 14-15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - cardiovascular (circulatory) system
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
1250 mg/kg
SEX/DURATION :
female 10 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - cytological changes (including somatic cell genetic material)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
1250 mg/kg
SEX/DURATION :
female 11 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Rodent - mouse Embryo
DOSE/DURATION :
1250 mg/kg
REFERENCE :
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 47,305,1981

Safety Information

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S36/37

[ RIDADR ]:
3276

[ RTECS ]:
UG0350000

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2926909090

Synthetic Route

Customs

[ HS Code ]: 2926909090

[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%


Related Compounds

  • Ethyl 2-{[5-(trifluoromethyl)pyridin-2-yl]amino}acetate
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide