4-Difluoromethoxy-3-hydroxybenzaldehyde

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Names

[ CAS No. ]:
151103-08-1

[ Name ]:
4-Difluoromethoxy-3-hydroxybenzaldehyde

[Synonym ]:
4-Difluoromethoxy-3-hydroxy-benzald; ehyde
4-Difluoromethoxy-3-hydroxybenzaldehyde
MFCD04406687
Benzaldehyde, 4-(difluoromethoxy)-3-hydroxy-
3-Hydroxy-4-difluoromethoxybenzaldehyde
4-(Difluoromethoxy)-3-hydroxybenzaldehyde

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
280.6±35.0 °C at 760 mmHg

[ Melting Point ]:
90 °C

[ Molecular Formula ]:
C8H6F2O3

[ Molecular Weight ]:
188.128

[ Flash Point ]:
123.5±25.9 °C

[ Exact Mass ]:
188.028503

[ PSA ]:
46.53000

[ LogP ]:
1.28

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.533

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335-H411

[ Precautionary Statements ]:
P261-P273-P305 + P351 + P338

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2913000090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Sodium chlorodifluoroacetate
  • 3,4-Dihydroxybenzaldehyde
  • Difluorochloromethane
  • 2-(4-(difluoromethoxy)-3-methoxyphenyl)-1,3-dioxolane
  • Methyl chlorodifluoroacetate
  • chlorodifluoroacetic acid
  • Water
  • 4-(Difluoromethoxy)-3-methoxybenzaldehyde
  • Vanillin

DownStream

  • 3-Cyclopentyloxy-4-difluoromethoxy-benzaldehyde
  • 3,4-Bis(difluoromethoxy)benzaldehyde
  • 4-(difluoromethoxy)-3-(cyclopropylmethoxy)-benzaldethyde
  • 3-Cyclopropylmethoxy-4-difluoromethoxybenzoic Acid
  • Roflumilast
  • 3-Cyclobutoxy-4-difluoromethoxy-benzaldehyde
  • 3-(Cyclopropylmethoxy)-4-(difluoromethoxy)benzoyl chloride
  • 4-(difluoromethoxy)-3-hydroxybenzoic acid

Customs

[ HS Code ]: 2913000090

[ Summary ]:
HS: 2913000090 halogenated, sulphonated, nitrated or nitrosated derivatives of products of heading 2912 Educational tariff:17.0% Tax rebate rate:9.0% Regulatory conditions:none Most favored nation tariff:5.5% General tariff:30.0%

Related Compounds

  • 4-(Difluoromethoxy)-3-iodobenzoic acid
  • 4-(difluoromethoxy)-3-(cyclopropylmethoxy)-benzaldethyde
  • 4-DIFLUOROMETHOXY-3-METHOXY-BENZOIC ACID
  • 4-(difluoromethoxy)-3-methylphenol
  • 4-(Difluoromethoxy)-3-methoxyaniline
  • 4-(Difluoromethoxy)-3-fluoroaniline(WS204099)
  • 2-(2-chlorophenyl)-N-((4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)methyl)acetamide
  • 1-(methylsulfonyl)-N-((4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)methyl)piperidine-4-carboxamide
  • 2-((4-fluorophenyl)thio)-N-((4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)methyl)acetamide
  • N-((4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)methyl)thiophene-3-carboxamide
  • 3-(phenylsulfonyl)-N-((4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)methyl)propanamide
  • 2-(4-(isopropylthio)phenyl)-N-((4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)methyl)acetamide
  • 3-(dimethylamino)-N-((4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)methyl)benzamide
  • 3-cyano-N-((4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)methyl)benzamide
  • 4-propyl-N-((4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)methyl)-1,2,3-thiadiazole-5-carboxamide
  • N-((4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)methyl)benzo[c][1,2,5]thiadiazole-5-carboxamide
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