2,6-Difluoropyridine

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Names

[ CAS No. ]:
1513-65-1

[ Name ]:
2,6-Difluoropyridine

[Synonym ]:
2,6-F2-C5H3N
Pyridine, 2,6-difluoro-
2,6-difluorpyridin
2,6-Difluoropyridine
2,6-di-fluoro-pyridine
2,6-difluoropyridin
2,6-difluorpyridine
2,5-DIFLUOROBENZOTRIFLUORIDE
EINECS 216-152-8
MFCD00006227
Pyridine,2,6-difluoro

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
134.3±20.0 °C at 760 mmHg

[ Molecular Formula ]:
C5H3F2N

[ Molecular Weight ]:
115.08

[ Flash Point ]:
33.9±0.0 °C

[ Exact Mass ]:
115.023354

[ PSA ]:
12.89000

[ LogP ]:
0.99

[ Vapour Pressure ]:
10.0±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.447

[ Storage condition ]:
Flammables area

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R10;R36/37/38

[ Safety Phrases ]:
S16-S26-S36/37/39-S37/39

[ RIDADR ]:
UN 1993 3/PG 3

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
2933399010

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Pyridine
  • 2,6-Dichloropyridine
  • 2,6-Diaminopyridine
  • 2,6-Difluoro-3-iodopyridine
  • 2-Chloropyridine

DownStream

  • 2,6-Pyridinedicarbonitrile
  • 6-Fluoro-2-pyridinecarbonitrile
  • 2-Fluoro-6-phenylpyridine
  • 2,6-Difluoronicotinic acid
  • 1-(2,6-difluoropyridin-3-yl)ethanone
  • Piperazine, 1-(6-fluoro-2-pyridinyl)- (9CI)
  • 3-Bromo-2,6-difluoropyridine
  • 2,6-Difluoro-3-nitropyridine
  • 2,6-Difluoro-3-iodopyridine
  • 6-fluoropyridine-2-sulfonyl chloride

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Cyclic poly (pyridine ether) s by the polycondensation of 2, 6-difluoropyridine with various diphenols. Kricheldorf HR, et al.

J. Polym. Sci. A Polym. Chem. 430(20) , 4781-89, (2005)

Multicyclic polyethers derived from 1, 1, 1-tris (4-hydroxyphenyl) ethane and 2, 6-dihalopyridines. Kricheldorf HR, et al.

J. Polym. Sci. A Polym. Chem. 42(22) , 5725-35, (2004)

Lithium diisopropylamide-mediated ortholithiation of 2-fluoropyridines: rates, mechanisms, and the role of autocatalysis.

J. Org. Chem. 78(9) , 4214-30, (2013)

Lithium diisopropylamide (LDA)-mediated ortholithiations of 2-fluoropyridine and 2,6-difluoropyridine in tetrahydrofuran at -78 °C were studied using a combination of IR and NMR spectroscopic and comp...


More Articles

Related Compounds

  • 2,6-difluoropyridine,hydrate
  • 4-Amino-2,6-difluoropyridine
  • 4-Bromo-2,6-difluoropyridine
  • 3-amino-2,6-difluoropyridine
  • 3-amino-2,6-difluoropyridine
  • 3-Bromo-2,6-difluoropyridine
  • 1-[(4,4-Dimethylpiperidin-1-yl)sulfonyl]pentan-2-amine
  • 2-amino-N-ethyl-N-methylpropane-1-sulfonamide
  • 4-[(1-ethylcyclopentyl)carbamoyl]-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid
  • 2-(3-Formamidooxan-3-yl)acetic acid
  • (1-{[(5-Chlorofuran-2-yl)methyl]sulfanyl}-3-methylbutan-2-yl)(methyl)amine
  • 1-(4-formyl-1-methyl-1H-pyrazol-3-yl)-1H-pyrazole-4-carboxamide
  • 2-[(4-Methyloxolan-3-yl)oxy]-1,3-thiazol-5-amine
  • 3-Amino-4-(2-hydroxyethoxy)pyridin-2-ol
  • (2S)-2-[(4S)-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-5,5,5-trifluoropentanamido]pentanoic acid
  • (4S)-4-[(2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanamido]-5,5,5-trifluoropentanoic acid
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