Oxamflatin

Suppliers

Names

[ Name ]:
Oxamflatin

[Synonym ]:
2-Penten-4-ynamide, N-hydroxy-5-[3-[(phenylsulfonyl)amino]phenyl]-, (2E)-
(2E)-N-hydroxy-5-{3-[(phenylsulfonyl)amino]phenyl}pent-2-en-4-ynamide
(2E)-N-Hydroxy-5-{3-[(phenylsulfonyl)amino]phenyl}-2-penten-4-ynamide
(2E)-5-[3-(Phenylsulfonylamino)phenyl]-pent-2-en-4-ynohydroxamic acid
(E)-5-[3-(benzenesulfonamido)phenyl]-N-hydroxypent-2-en-4-ynamide

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C₁₇H₁₄N₂O₄S

[ Molecular Weight ]:
342.369

[ Exact Mass ]:
342.067413

[ PSA ]:
103.88000

[ LogP ]:
3.26

[ Index of Refraction ]:
1.686

[ Storage condition ]:
2-8℃

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2935009090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Dehydroxyamino Oxamflatin Acid
tert-Butyl (3-iodophenyl)carbamate

DownStream

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Articles

Survival motor neuron gene 2 silencing by DNA methylation correlates with spinal muscular atrophy disease severity and can be bypassed by histone deacetylase inhibition.

Hum. Mol. Genet. 18 , 304-17, (2009)

Spinal muscular atrophy (SMA), a common neuromuscular disorder, is caused by homozygous absence of the survival motor neuron gene 1 (SMN1), while the disease severity is mainly influenced by the numbe...

OXAMFLATIN
Oxamflatin
Dehydroxyamino Oxamflatin Acid
3-Iodo-1-(2-methoxyethyl)pyrrolo[3,2-c]pyridine
4-(4-(3-Cyclohexylpropoxy)-2-oxopyridin-1(2h)-yl)-2-methyl-2-(methylsulfonyl)butanoic acid
Butanamide, 2-amino-4-[ethyl(4-fluorophenyl)amino]-2-methyl-
N-(2-(benzyloxy)ethyl)-1H-imidazole-1-carboxamide
Ethyl 4-chloro-1,5-dimethyl-6-oxo-1,6-dihydropyridazine-3-carboxylate
8-phenyl-2,3-dihydrodibenzo[b,d]thiophen-4(1H)-one
6-{[(Benzyloxy)carbonyl](methyl)amino}hexanoic acid
2-(4-((Tetrahydrofuran-2-yl)methyl)piperazin-1-yl)ethan-1-ol
2-Amino-3-(3-difluoromethoxy-phenyl)-propionic acid ethyl ester
2-{4-[(7-{3-[Ethyl(2-hydroxyethyl)amino]propoxy}quinazolin-4-yl)amino]-1h-pyrazol-1-yl}-n-(3-fluorophenyl)acetamide

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