2-(TERT-BUTOXYCARBONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID

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Names

[ CAS No. ]:
151838-62-9

[ Name ]:
2-(TERT-BUTOXYCARBONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID

[Synonym ]:
Boc-L-Tic-OH
Boc-DL-Tic-OH
2-{[(2-Methyl-2-propanyl)oxy]carbonyl}-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid
dl-2-t-butoxycarbonyl-3-carboxy-1,2,3,4-tetrahydroisoquinoline
N-Boc-L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
Boc-Tic-OH
2-(tert-Butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
2,3(1H)-Isoquinolinedicarboxylic acid, 3,4-dihydro-, 2-(1,1-dimethylethyl) ester

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
437.6±45.0 °C at 760 mmHg

[ Melting Point ]:
125-126ºC

[ Molecular Formula ]:
C15H19NO4

[ Molecular Weight ]:
277.316

[ Flash Point ]:
218.5±28.7 °C

[ Exact Mass ]:
277.131409

[ PSA ]:
66.84000

[ LogP ]:
2.40

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.556

Safety Information

[ Hazard Codes ]:
Xi: Irritant;

[ HS Code ]:
2933499090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Di-tert-butyl dicarbonate
  • h-dl-tic-oh
  • 1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
  • 2-Cyano-N-Boc-DL-phenylalanine
  • BOC-ON
  • 2-Cyanobenzyl bromide
  • 2-(trimethylsilyl)ethyl 2-((tert-butoxycarbonyl)amino)-3-(2-cyanophenyl)propanoate
  • [1,2,3,4]-tetrahydroisoquinoline-2-carboxylic acid

DownStream

  • tert-Butyl 3-formyl-3,4-dihydroisoquinoline-2(1H)-carboxylate
  • tert-Butyl 3-(hydroxymethyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate

Customs

[ HS Code ]: 2933499090

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • (3S)-3-Hydroxy-N-methyl-3-phenylpropanamide
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide