levallorphan
Suppliers
Names
[ CAS No. ]:
152-02-3
[ Name ]:
levallorphan
[Synonym ]:
EINECS 205-799-1
Lorfan
Levallorphane
Levalorfano [INN-Spanish]
Levallorphanum
Levallorphane [INN-French]
Levalorfano
Levallofano [DCIT]
Naloxiphan
17-allyl-morphinan-3-ol
Chemical & Physical Properties
[ Density]:
1.14g/cm3
[ Boiling Point ]:
433.5ºC at 760mmHg
[ Molecular Formula ]:
C19H25NO
[ Molecular Weight ]:
283.40800
[ Flash Point ]:
214.2ºC
[ Exact Mass ]:
283.19400
[ PSA ]:
23.47000
[ LogP ]:
3.57450
[ Vapour Pressure ]:
4.02E-08mmHg at 25°C
[ Index of Refraction ]:
1.614
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QD0350000
- CHEMICAL NAME :
- Morphinan-3-ol, 17-allyl-, (-)-
- CAS REGISTRY NUMBER :
- 152-02-3
- LAST UPDATED :
- 199512
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C19-H25-N-O
- MOLECULAR WEIGHT :
- 283.45
- WISWESSER LINE NOTATION :
- T6 G666/FQ 2AF Q FX ONT&TTJ IQ O2U1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 949 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZIAQ "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973 Volume(issue)/page/year: -,-,1965
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 185 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZIAQ "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973 Volume(issue)/page/year: -,140,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 184 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZIAQ "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973 Volume(issue)/page/year: -,-,1965
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877- Volume(issue)/page/year: 281,321,1976 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4763 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 103 (estimated) No. of Female Employees: 52 (estimated)