Dp44mT
Suppliers
Names
[ CAS No. ]:
152095-12-0
[ Name ]:
Dp44mT
[Synonym ]:
2-(Di-2-pyridinylmethylene)-N,N-dimethylhydrazinecarbothioamide
2-(dipyridin-2-ylmethylidene)-N,N-dimethylhydrazinecarbothioamide
Hydrazinecarbothioamide,2-(di-2-pyridinylmethylene)-N,N-dimethyl
Iron Chelator,Dp44mT
Hydrazinecarbothioamide, 2-(di-2-pyridinylmethylene)-N,N-dimethyl-
2,N-dimethylsemicarbazone
Dp44mT
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
438.4±43.0 °C at 760 mmHg
[ Molecular Formula ]:
C14H15N5S
[ Molecular Weight ]:
285.367
[ Flash Point ]:
218.9±28.2 °C
[ Exact Mass ]:
285.104828
[ PSA ]:
92.54000
[ LogP ]:
1.21
[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C
[ Index of Refraction ]:
1.635
[ Storage condition ]:
-20℃
MSDS
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301
[ Precautionary Statements ]:
P301 + P310
[ RIDADR ]:
UN 2811 6.1 / PGIII
Articles
Oncotarget 6 , 10374-98, (2015)
Di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT) demonstrates potent anti-cancer activity. We previously demonstrated that 14C-Dp44mT enters and targets cells through a carrier/receptor-me...
Oncotarget 6 , 8851-74, (2015)
N-myc downstream regulated gene-1 (NDRG1) is a potent metastasis suppressor that plays a key role in regulating signaling pathways involved in mediating cancer cell invasion and migration, including t...
Mol. Cell. Endocrinol. 407 , 74-84, (2015)
High levels of plasma free fatty acid are thought to contribute to the loss of pancreatic beta-cells in type 2 diabetes. In particular, saturated fatty acid such as palmitate or stearate can induce ap...