5-Thiazolidineethanol,3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-

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Names

[ Name ]:
5-Thiazolidineethanol,3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-

[Synonym ]:
2-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazolidin-5-yl}ethanol
2-[3-(4-Amino-2-methyl-pyrimidin-5-ylmethyl)-4-methyl-thiazolidin-5-yl]-aethanol
2-[3-(4-amino-2-methyl-pyrimidin-5-ylmethyl)-4-methyl-thiazolidin-5-yl]-ethanol
Tetrahydrothiamine
3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-4-methyl-5-thiazolidineethanol
tetrahydro-thiamin
5-thiazolidineethanol,3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl

Chemical & Physical Properties

[ Density]:
1.233g/cm3

[ Boiling Point ]:
446ºC at 760mmHg

[ Molecular Formula ]:
C₁₂H₂₀N₄OS

[ Molecular Weight ]:
268.37800

[ Flash Point ]:
223.5ºC

[ Exact Mass ]:
268.13600

[ PSA ]:
100.57000

[ LogP ]:
1.53210

[ Vapour Pressure ]:
9.74E-09mmHg at 25°C

[ Index of Refraction ]:
1.61

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XJ5952000

CHEMICAL NAME :: 5-Thiazolidineethanol, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-4-methyl-

CAS REGISTRY NUMBER :: 15233-41-7

LAST UPDATED :: 199706

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C12-H20-N4-O-S

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 430 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: VABBA3 Vestsi Akademii Navuk Belaruskai SSR, Seryya Biyalagichnykh Navuk. Proceedings of the Academy of Sciences of the Belorussian SSR, Biological Sciences Series. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) No. 1- 1956- Volume(issue)/page/year: (6),54,1977

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: VABBA3 Vestsi Akademii Navuk Belaruskai SSR, Seryya Biyalagichnykh Navuk. Proceedings of the Academy of Sciences of the Belorussian SSR, Biological Sciences Series. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) No. 1- 1956- Volume(issue)/page/year: (6),54,1977 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1200 mg/kg/30D-I

TOXIC EFFECTS :: Brain and Coverings - other degenerative changes Blood - changes in spleen Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other Enzymes

REFERENCE :: VABBA3 Vestsi Akademii Navuk Belaruskai SSR, Seryya Biyalagichnykh Navuk. Proceedings of the Academy of Sciences of the Belorussian SSR, Biological Sciences Series. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) No. 1- 1956- Volume(issue)/page/year: (6),54,1977

Safety Information

[ HS Code ]:
2934999090

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
B-[4-(2-cyclopropyl-1h-imidazol-5-yl)phenyl]boronic acid
2-Piperidinone, 1-methyl-5-[(2-pyridinylmethyl)amino]-
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
tert-Butyl-DL-alanine