Imatinib (STI571)

Suppliers

Names

[ Name ]:
Imatinib (STI571)

[Synonym ]:
Benzamide, 4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]- (9CI)
Imatinib
STI571
Imatinib (STI571)
Benzamide, 4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-
4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
4-[(4-methylpiperazin-1-yl)methyl]-N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide
1iep
UNII-BKJ8M8G5HI
Benzamide, 4-((4-methyl)-1-piperazinyl)methyl)-N-(4-methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)phenyl)-
MFCD05662257
4-[(4-Methyl-1-piperazinyl)methyl]-N-(4-methyl-3-{[4-(3-pyridinyl)-2-pyrimidinyl]amino}phenyl)benzamide
Imatinib free base
1xbb

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
451°C

[ Melting Point ]:
113°C

[ Molecular Formula ]:
C₂₉H₃₁N₇O

[ Molecular Weight ]:
493.603

[ Flash Point ]:
196°C

[ Exact Mass ]:
493.259003

[ PSA ]:
86.28000

[ LogP ]:
2.48

[ Vapour Pressure ]:
6.03E-24mmHg at 25°C

[ Index of Refraction ]:
1.672

[ Storage condition ]:
Refrigerator

Safety Information

[ Hazard Codes ]:
T,N

[ Risk Phrases ]:
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed . R40:Limited evidence of a carcinogenic effect. R48/23/24:Toxic: danger of serious damage to health by prolonged exposure through inhalation and in contact with skin . R51/53:Toxic to aq

[ Safety Phrases ]:
S28-S36/37-S45-S61-S24/25-S23-S53

[ RIDADR ]:
UN 1662 6.1/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine
4-(4-Methylpiperazin-1-ylmethyl)benzoyl chloride
Methyl 4-[(4-methyl-1-piperazinyl)methyl]benzoate
4-(4-methyl piperazin-1-ylmethyl)-benzoic acid ethyl ester
4-(4-methyl-piperazin-1-methyl)-benzoic acid benzyl ester
4-(4-methyl-piperazin-1-methyl)-benzoic acid propyl ester
3-Pyridylboronic acid

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%