IB-MECA

Suppliers

Names

[ CAS No. ]:
152918-18-8

[ Name ]:
IB-MECA

[Synonym ]:
UNII-30679UMI0N
Piclidenoson
(2S,3S,4R,5R)-3,4-Dihydroxy-5-{6-[(3-iodobenzyl)amino]-9H-purin-9-yl}-N-methyltetrahydro-2-furancarboxamide
IBMECA
(2S,3S,4R,5R)-3,4-Dihydroxy-5-{6-[(3-iodobenzyl)amino]-9H-purin-9-yl}-N-methyltetrahydrofuran-2-carboxamide (non-preferred name)
CF 101
3-IB-Meca
IB-MECA
CF101

Chemical & Physical Properties

[ Density]:
2.0±0.1 g/cm3

[ Molecular Formula ]:
C18H19IN6O4

[ Molecular Weight ]:
510.286

[ Exact Mass ]:
510.051239

[ PSA ]:
134.42000

[ LogP ]:
2.08

[ Index of Refraction ]:
1.808

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Benzylamine, m-iodo-, hydrochloride
  • 1-(6-Chloro-9H-purin-9-yl)-1-deoxy-2,3-O-isopropylidene-beta-D-ribofuranuronoyl chloride
  • 1-(6-Chloro-9H-purin-9-yl)-1-deoxy-N-methyl-2,3-O-isopropylidene-beta-D-ribofuranuronamide
  • 3-Iodobenzaldehyde
  • b-D-Ribofuranuronamide,1-(6-amino-9H-purin-9-yl)-1-deoxy-N-methyl-

DownStream

  • 2-CL-IB-MECA

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Equilibrium and kinetic selectivity profiling on the human adenosine receptors.

Biochem. Pharmacol. 105 , 34-41, (2016)

Classical evaluation of target selectivity is usually undertaken by measuring the binding affinity of lead compounds against a number of potential targets under equilibrium conditions, without conside...

Activation of A1, A2A, or A3 adenosine receptors attenuates lung ischemia-reperfusion injury.

J. Thorac. Cardiovasc. Surg. 140(2) , 440-6, (2010)

Adenosine and the activation of specific adenosine receptors are implicated in the attenuation of inflammation and organ ischemia-reperfusion injury. We hypothesized that activation of A(1), A(2A), or...

Activation of adenosine low-affinity A3 receptors inhibits the enteric short interplexus neural circuit triggered by histamine.

Am. J. Physiol. Gastrointest. Liver Physiol. 297(6) , G1147-62, (2009)

We tested the novel hypothesis that endogenous adenosine (eADO) activates low-affinity A3 receptors in a model of neurogenic diarrhea in the guinea pig colon. Dimaprit activation of H2 receptors was u...


More Articles

Related Compounds

  • IB-MECA
  • CI-IB-MECA
  • 2-Cl-IB-MECA
  • AB-MECA
  • N-IB-DG
  • Petrosyne Ib
  • 7-bromo-N-(3-chloro-4-fluorophenyl)-6-fluoropyrido[3,2-d]pyrimidin-4-amine
  • B-[2,6-dimethoxy-4-(methoxymethyl)phenyl]Boronic acid
  • 2-N-(2,4-dichlorophenyl)pyridine-2,3-diamine
  • 2-N-(2,5-dimethoxyphenyl)pyridine-2,3-diamine
  • N2-(3-Methoxy-4-methylphenyl)-2,3-pyridinediamine
  • 2-(2-Methylcyclohexyl)aniline
  • 4-((3-Aminopyridin-2-yl)amino)benzoic acid
  • 5-bromo-4-(4-bromo-2-fluorophenylamino)-N-(cyclopropylmethoxy)-1-methyl-6-oxo-1,6-dihydropyridazine-3-carboxamide
  • 2-Methoxy-4-[(1-methylethoxy)methyl]phenol
  • 3-[(2E)-3-(4-chlorophenyl)prop-2-enoyl]-7-methoxy-2H-chromen-2-one
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