(2S,3S,4R,5R)-5-[6-[(4-amino-3-iodophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-N-methyloxolane-2-carboxamide

Names

[ CAS No. ]:
152918-27-9

[ Name ]:
(2S,3S,4R,5R)-5-[6-[(4-amino-3-iodophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-N-methyloxolane-2-carboxamide

[Synonym ]:
3-Iodo-4-aminobenzyl-5'-N-methylcarboxamidoadenosine
I-AB-MECA

Chemical & Physical Properties

[ Density]:
2.066g/cm3

[ Molecular Formula ]:
C18H20IN7O4

[ Molecular Weight ]:
525.30000

[ Exact Mass ]:
525.06200

[ PSA ]:
163.93000

[ LogP ]:
1.48490

[ Index of Refraction ]:
1.842

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

125I-4-aminobenzyl-5'-N-methylcarboxamidoadenosine, a high affinity radioligand for the rat A3 adenosine receptor.

Mol. Pharmacol. 45 , 978-982, (1994)

The rat A3 adenosine receptor (AR) is a recently characterized AR subtype cloned from testis and brain cDNA libraries. N6-2-(4-Amino-3-[125I]iodophenyl)ethyladenosine, a high affinity A1AR agonist, ha...

A role for central A3-adenosine receptors. Mediation of behavioral depressant effects.

FEBS Lett. 336 , 57-60, (1993)

The behavioral effects of a selective A3 adenosine receptor agonist 3-IB-MECA (N6-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine) in mice and the localization of radioligand binding sites in mouse bra...

The effects of adenosine A3 receptor stimulation on seizures in mice.

Eur. J. Pharmacol. 275 , 23-29, (1995)

We have previously shown that acute preischemic adenosine A3 receptor stimulation results in an increased postischemic damage, while chronic stimulation of this receptor diminishes it. Since several p...


More Articles

Related Compounds

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  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
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  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
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  • (3,4-dimethoxyphenyl)[4-(3-fluoro-4-methylphenyl)-1,1-dioxido-4H-1,4-benzothiazin-2-yl]methanone
  • (Z)-1-(3-fluorobenzyl)-3-(((2-(trifluoromethyl)phenyl)amino)methylene)-1H-thieno[3,2-c][1,2]thiazin-4(3H)-one 2,2-dioxide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine