Tyrphostin AG 1112

[ Molecular Formula ]:
C₁₅H₁₀N₆

[ Molecular Weight ]:
274.28

[ Appearance of Characters ]:
solid

[ Storage condition ]:
−20°C

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
36/37/38-40

[ Safety Phrases ]:
26-36/37

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

Protein kinase inhibitors as a therapeutic modality.

Acc. Chem. Res. 36(6) , 462-9, (2003)

Most of the signal transduction pathways are mediated by protein kinases regulating every aspect of cell function. Mutations which deregulate their expression or their function or both result in cance...

Tyrphostin-induced inhibition of p210bcr-abl tyrosine kinase activity induces K562 to differentiate.

Blood 82(12) , 3524-9, (1993)

We report on the potency of two Tyrphostin tyrosine kinase blockers, AG 1112 and AG 568, to inhibit p210bcr-abl tyrosine kinase activity in K562 cells, concomitant with the induction of erythroid diff...

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