NS-1619

Suppliers

Names

[ Name ]:
NS-1619

[Synonym ]:
Lopac-N-170
1-(2-Hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-1H-benzo[d]imidazol-2(3H)-one
3-[2-hydroxy-5-(trifluoromethyl)phenyl]-6-(trifluoromethyl)-1H-benzimidazol-2-one
1,3-Dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-2H-benzimidazol-2-one
NS-1619

Chemical & Physical Properties

[ Density]:
1.563g/cm3

[ Melting Point ]:
234 °C(dec.)

[ Molecular Formula ]:
C₁₅H₈F₆N₂O₂

[ Molecular Weight ]:
362.22700

[ Exact Mass ]:
362.04900

[ PSA ]:
58.02000

[ LogP ]:
4.06200

[ Index of Refraction ]:
1.538

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933990090

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Potassium channel openers prevent palmitate-induced insulin resistance in C2C12 myotubes.

Arch. Biochem. Biophys. 541 , 47-52, (2014)

Insulin resistance (IR) of muscle cells is an early symptom of type 2 diabetes. It often results from excessive lipid accumulation in muscle fibers which under in vitro experimental conditions may be ...

Potassium ion channels and allergic asthma.

Adv. Exp. Med. Biol. 838 , 35-45, (2015)

High-conductive calcium-sensitive potassium channels (BK+Ca) and ATP-sensitive potassium (K+ATP) channels play a significant role in the airway smooth muscle cell and goblet cell function, and cytokin...

High glucose alters apoptosis and proliferation in HEK293 cells by inhibition of cloned BK Ca channel.

J. Cell Physiol. 226(6) , 1660-75, (2011)

It has been reported that diabetic vascular dysfunction is associated with impaired function of large conductance Ca(2+) -activated K(+) (BK(Ca) ) channels. However, it is unclear whether impaired BK(...

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