1-(2,6-Dichlorophenyl)-2-indolinone

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Names

[ CAS No. ]:
15362-40-0

[ Name ]:
1-(2,6-Dichlorophenyl)-2-indolinone

[Synonym ]:
1-(2,6-Dichlorophenyl)-1,3-dihydro-2H-indol-2-one
Diclofenac Amide
2H-Indol-2-one, 1-(2,6-dichlorophenyl)-1,3-dihydro-
EINECS 239-399-3
(N-(2,6-Dichlorophenyl)-2-indolinone
1-(2,6-Dichlorophenyl)-2-oxoindoline
1-(2,6-Dichloro-phenyl)-1,3-dihydro-indol-2-one
1-(2,6-dichlorophenyl)-3H-indol-2-one
N-(2,6-Dichlorophenyl)-2-indolinone
1-(2,6-dichlorophenyl)-2-indolone
1-(2,6-Dichlorophenyl)indolin-2-one
1-(2,6-dichlorophenyl)-2-indolinone
1-(2,6-Dichlorophenyl)oxindole
Diclofenac impurity A
Aceclofenac Impurity 9

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
488.6±45.0 °C at 760 mmHg

[ Melting Point ]:
115-119°C

[ Molecular Formula ]:
C14H9Cl2NO

[ Molecular Weight ]:
278.133

[ Flash Point ]:
249.3±28.7 °C

[ Exact Mass ]:
277.006134

[ PSA ]:
20.31000

[ LogP ]:
3.00

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.661

[ Storage condition ]:
Refrigerator

[ Stability ]:
Stability

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NM3259200
CHEMICAL NAME :
2H-Indol-2-one, 1,3-dihydro-1-(2,6-dichlorophenyl)-
CAS REGISTRY NUMBER :
15362-40-0
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C14-H9-Cl2-N-O
MOLECULAR WEIGHT :
278.14

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 21,275,1987

Safety Information

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933790090

Synthetic Route

Precursor & DownStream

Precursor

  • 2-Chloro-N-(2,6-dichlorophenyl)-N-phenylacetamide
  • Diclofenac sodium
  • 1-(2,6-dichlorophenyl)-3-(methylthio)oxindole
  • 2,6-Dichloro-N-phenylaniline
  • Diclofenac
  • N-(2,6-dichlorophenyl)-2-methylsulfanyl-N-phenylacetamide
  • N-(2,6-dichlorophenyl)-α-(methylsulfinyl)acetanilide
  • 2-chloro-n-(2,6-dichlorophenyl)acetamide
  • Methanol

DownStream

  • 2-[[(3E)-1-(2,6-dichlorophenyl)-3-(dimethylaminomethylidene)-2-oxoindol-6-yl]methylidene]propanedinitrile
  • 1-(2,6-dichlorophenyl)-3-(hydroxymethylidene)-2-oxoindole-6-carbaldehyde
  • Indole-3,6-dicarboxaldehyde
  • Diclofenac sodium

Customs

[ HS Code ]: 2933790090

[ Summary ]:
2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%


Related Compounds

  • 1-(2,6-Dichlorophenyl)-2-indolinone
  • 1-(2,6-dichlorophenyl)-2-sulfanylidenepyridine-3-carbaldehyde
  • 1-(2,6-dichlorophenyl)-2,4-dihydro-1H-isoquinolin-3-one
  • 1-[(2,6-dichlorophenyl)-(2-hydroxynaphthalen-1-yl)methyl]naphthalen-2-ol
  • 1-(2,6-Dichlorophenyl)-2-methyl-1-propanone
  • 1-(2,6-Dichlorophenyl)-2-pentanone