6-methyl-3-[2-(2-methylpropylsulfanyl)ethyl]-1H-pyrimidine-2,4-dione,platinum(2+),dichloride

Names

[ CAS No. ]:
153660-61-8

[ Name ]:
6-methyl-3-[2-(2-methylpropylsulfanyl)ethyl]-1H-pyrimidine-2,4-dione,platinum(2+),dichloride

Chemical & Physical Properties

[ Molecular Formula ]:
C22H36Cl2N4O4PtS2

[ Molecular Weight ]:
750.66000

[ Exact Mass ]:
749.12000

[ PSA ]:
166.50000

[ LogP ]:
5.77090

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TP2246575
CHEMICAL NAME :
Platinum, bis(6-methyl-3-(2-((2-methylpropyl)thio)ethyl)-2,4-(1 H,3H)-pyrimidinedione -S) dichloro-, (SP-4-1)-
CAS REGISTRY NUMBER :
153660-61-8
LAST UPDATED :
199509
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C22-H36-Cl2-N4-O4-Pt-S2
MOLECULAR WEIGHT :
750.73

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 27,776,1993

Related Compounds

  • (S)-Methyl 2-(3-chlorobenzo[b]thiophene-2-carboxamido)-3-phenylpropanoate
  • 3-Benzyl-5-(3-methylpiperazin-1-yl)-1,2,4-thiadiazole
  • (2R)-2-Methyl-3-pyridin-3-ylpropan-1-amine
  • 3-(4-Chlorobenzyl)-5-(3-methylpiperazin-1-yl)-1,2,4-thiadiazole
  • 4,5,6,7-Tetrahydro-4-(4-methylphenyl)thieno[3,2-c]pyridine
  • N-(1-cyanocyclopentyl)-2-{[2-fluoro-4-(propan-2-yloxy)phenyl]amino}acetamide
  • 2-(Aminomethyl)-N-(2-hydroxyethyl)-N-(1-methylethyl)benzenemethanesulfonamide
  • N-(1-cyano-1-methylethyl)-2-[4-(ethanesulfonyl)piperazin-1-yl]-N-methylacetamide
  • 1-(4-fluorobenzyl)-3-(2-(2-methyl-1H-imidazol-1-yl)ethyl)urea
  • 1-(2-chlorophenyl)-3-(2-(2-methyl-1H-imidazol-1-yl)ethyl)urea
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