2-Deoxy-D-glucose

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Names

[ CAS No. ]:
154-17-6

[ Name ]:
2-Deoxy-D-glucose

[Synonym ]:
2-DEOXY-D-ARABINOHEXOSE
D-arabino-Hexose, 2-deoxy-
2-Deoxy-D-arabino-hexose
2-Deoxy-D-glucose
2-deoxy-d-arabino-hexos
MFCD00151328
D-Arabino-2-deoxyhexose
EINECS 205-823-0

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
456.7±45.0 °C at 760 mmHg

[ Melting Point ]:
146-147ºC

[ Molecular Formula ]:
C6H12O5

[ Molecular Weight ]:
164.156

[ Flash Point ]:
244.1±25.2 °C

[ Exact Mass ]:
164.068466

[ PSA ]:
97.99000

[ LogP ]:
-3.07

[ Vapour Pressure ]:
0.0±2.5 mmHg at 25°C

[ Index of Refraction ]:
1.534

[ Storage condition ]:
2~8℃

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MQ3325000
CHEMICAL NAME :
D-arabino-Hexose, 2-deoxy-
CAS REGISTRY NUMBER :
154-17-6
BEILSTEIN REFERENCE NO. :
1723331
LAST UPDATED :
199701
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C6-H12-O5
MOLECULAR WEIGHT :
164.18
WISWESSER LINE NOTATION :
VH1YQYQYQ1Q -D-ARABINO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 39,327,1981
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 17,814,1965 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
2 gm/kg
SEX/DURATION :
female 7-8 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
REFERENCE :
85DJA5 "Malformations Congenitales des Mammiferes," Tuchmann-Duplessis, H., Paris, Masson et Cie, 1971 Volume(issue)/page/year: -,95,1971
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
4 gm/kg
SEX/DURATION :
female 7-14 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
REFERENCE :
85DJA5 "Malformations Congenitales des Mammiferes," Tuchmann-Duplessis, H., Paris, Masson et Cie, 1971 Volume(issue)/page/year: -,95,1971
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
2 gm/kg
SEX/DURATION :
female 7-10 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 40,143,1989

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
MQ3325000

[ HS Code ]:
2912491000

Synthetic Route

Precursor & DownStream

Precursor

  • 2,3-Dideoxy-4,5:6,7-di-O-isopropylidene-D-arabino-heptose
  • 2-deoxy-4,5-O-isopropylidene-D-arabino-hexose dimethyl acetal
  • patrinoside-aglycone-11-O-2'-deoxy-β-D-glucopyranoside
  • 6-O-benzoyl-2,3:4,5-di-O-isopropylidene-D-glucose diethyl dithioacetal
  • 2-deoxy-4,5-O-isopropylidene-D-arabino-hexose diethyl dithioacetal
  • 2-deoxy-4,5-O-isopropylidene-D-lyxo-hex-1-enose diethyl dithioacetal
  • 2,3:4,5-di-O-isopropylidene-D-glucose diethyl dithioacetal
  • ((4R,5S)-5-((R)-1-acetoxy-3,3-dimethoxypropyl)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl acetate

DownStream

  • Formic Acid
  • D-arabinitol
  • [2-oxo-2-(1H-pyrrol-2-yl)ethyl] benzoate
  • 3-Hydroxy-2-Methylpyridine
  • 2-Acetyl-1H-pyrrole
  • 6,6-bis(ethylsulfanyl)hexane-1,2,3,4-tetrol
  • b-D-arabino-Hexopyranose,2-deoxy-, 1,3,4,6-tetraacetate
  • a-D-arabino-Hexopyranose,2-deoxy-, 1,3,4,6-tetraacetate

Customs

[ HS Code ]: 2912491000

[ Summary ]:
2912491000. other aldehyde-alcohols. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

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