Phenylephrine hydrochloride

Suppliers

Names

[ CAS No. ]:
154-86-9

[ Name ]:
Phenylephrine hydrochloride

[Synonym ]:
DL-Phenylephrine Hydrochloride
3-[1-Hydroxy-2-(methylamino)ethyl]phenol hydrochloride (1:1)
Benzenemethanol, 3-hydroxy-α-[(methylamino)methyl]-, hydrochloride (1:1)
Phenylephrine hydrochloride
EINECS 205-835-6
PHENYLEPHRINE HCL

Chemical & Physical Properties

[ Boiling Point ]:
341.1ºC at 760 mmHg

[ Melting Point ]:
144ºC

[ Molecular Formula ]:
C9H14ClNO2

[ Molecular Weight ]:
203.666

[ Flash Point ]:
163.4ºC

[ Exact Mass ]:
203.071304

[ PSA ]:
52.49000

[ LogP ]:
1.83790

[ Vapour Pressure ]:
3.18E-05mmHg at 25°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DO7600000
CHEMICAL NAME :
Benzyl alcohol, m-hydroxy-alpha-((methylamino)methyl)-, hydrochloride, (+-)-
CAS REGISTRY NUMBER :
154-86-9
LAST UPDATED :
198706
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C9-H13-N-O2.Cl-H
MOLECULAR WEIGHT :
203.69
WISWESSER LINE NOTATION :
QR CYQ1M1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
420 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 89,382,1947
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - excitement Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 162,46,1931

Safety Information

[ Risk Phrases ]:
22-36/37/38

[ Safety Phrases ]:
26-36/37/39

[ RTECS ]:
DO7600000

[ HS Code ]:
2922509090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Phenylephrine hydrochloride

DownStream

  • 3-[2-(methylamino)ethyl]phenol,hydrochloride
  • Phenylephrine hydrochloride

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • Phenylephrine hydrochloride
  • Phenylephrine hydrochloride
  • L-phenylephrine hydrochloride
  • Norphenylephrine hydrochloride
  • (R)-(-)-phenylephrine hydrochloride
  • 3-<(pivalyloxy)methyl>phenylephrine hydrochloride
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • Ethyl 3-(3-chloro-4-(trifluoromethyl)phenyl)acrylate
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide