(S)-3,4-Dihydro-4-hydroxy-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide

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Names

[ CAS No. ]:
154127-42-1

[ Name ]:
(S)-3,4-Dihydro-4-hydroxy-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide

[Synonym ]:
(4S)-4-hydroxy-2-(3-methoxypropyl)-1,1-dioxo-3,4-dihydrothieno[3,2-e]thiazine-6-sulfonamide
(S)-3,4-Dihydro-4-hydroxy-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide
Brinzolamide Impurity 5

Chemical & Physical Properties

[ Density]:
1.575 g/cm3

[ Boiling Point ]:
612.4ºC at 760 mmHg

[ Molecular Formula ]:
C10H16N2O6S3

[ Molecular Weight ]:
356.43900

[ Flash Point ]:
324.2ºC

[ Exact Mass ]:
356.01700

[ PSA ]:
172.00000

[ LogP ]:
2.26950

[ Vapour Pressure ]:
7.49E-16mmHg at 25°C

[ Index of Refraction ]:
1.615

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2935009090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (4S)-3,4-Dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazin-4-ol 1,1-Dioxide
  • (S)-6-Chloro-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazin-4-ol 1,1-dioxide
  • 3,4-Dihydro-2-(3-methoxypropyl)-4-oxo-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide
  • dea
  • 3-Acetyl-2,5-dichlorothiophene
  • 1-(2-(benzylthio)-5-chlorothiophen-3-yl)ethanone

DownStream

  • Brinzolamide

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%