rel-Tranylcypromine

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Names

[ CAS No. ]:
155-09-9

[ Name ]:
rel-Tranylcypromine

[Synonym ]:
(1R,2S)-2-Phenylcyclopropanamine
2-Phenyl-1-aminocyclopropane, trans-
Tranylcypromine
Tranylcypromine (base and/or unspecified salts)
EINECS 205-841-9
(-)-Tranylcypromine
(1R,2S)-2-phenylcyclopropan-1-amine
Parnitene
SKF Trans-385
(1R)-2-Phenylcyclopropanamine
Cyclopropanamine,2-phenyl-,(1R,2S)-rel
Cyclopropanamine, 2-phenyl-, trans-
Tylciprine
dl-Tranylcypromine
Cyclopropanamine, 2-phenyl-, (1R,2S)-
Parnate
UNII:3E3V44J4Z9
Cyclopropanamine, 2-phenyl-, (1R)-
Cyclopropanamine, 2-phenyl-, (1R-trans)- (9CI)
(-)-2-phenylcyclopropyl-1-amine

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
218.3±29.0 °C at 760 mmHg

[ Molecular Formula ]:
C9H11N

[ Molecular Weight ]:
133.190

[ Flash Point ]:
90.8±19.6 °C

[ Exact Mass ]:
133.089142

[ PSA ]:
26.02000

[ LogP ]:
1.25

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.584

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GZ2450100
CHEMICAL NAME :
Cyclopropylamine, 2-phenyl-, trans-(+-)-
CAS REGISTRY NUMBER :
155-09-9
BEILSTEIN REFERENCE NO. :
3195803
LAST UPDATED :
199803
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C9-H11-N
MOLECULAR WEIGHT :
133.21

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - man
DOSE/DURATION :
5714 ug/kg
TOXIC EFFECTS :
Cardiac - arrhythmias (including changes in conduction)
REFERENCE :
JATOD3 Journal of Analytical Toxicology. (Preston Pub. Inc., POB 48312, Niles, IL 60648) V.1- 1977- Volume(issue)/page/year: 20,301,1996
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
64 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 166,449,1967
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
25 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - excitement
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 21,1727,1971

Safety Information

[ HS Code ]:
2921499090

Precursor & DownStream

Precursor

DownStream

  • Cinnamic aldehyde
  • methyl(3-phenylpropyl)amine
  • 6-fluoro-7-(1-piperazinyl)-1-(2'-phenyl-1'-cyclopropyl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid

Customs

[ HS Code ]: 2921499090

[ Summary ]:
2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%


Related Compounds

  • rel-(1R,4E,pS)-Cyclooct-4-enol
  • rel-Phenyl(3α*-phenyl-3-methyloxirane-2α*-yl) ketone
  • rel-(1R,2S,4S)-norbornan-2-ol
  • rel-(2S,2'R,3'R)-2(3-Hydroxy-2-methoxy-2,3-dihydrobenzofuran-3-yl)-2-methoxy-3(2H)-benzofuranon
  • rel-Benzyl (1R,3S)-3-hydroxycyclopentane-1-carboxylate
  • rel-(2R,3S)-3-(2-ethoxyphenoxy)-3-phenylpropane-1,2-diol
  • 4-(Difluoromethyl)-3-methoxy-5-nitropicolinoyl chloride
  • 4-(Difluoromethyl)-6-(hydroxymethyl)-5-methoxypyridin-2-ol
  • 4-(Difluoromethyl)-5-fluoro-2-methoxy-3-(trifluoromethoxy)pyridine
  • 4-(Difluoromethyl)-2-(trifluoromethyl)pyridine-3-sulfonamide
  • (4-(Difluoromethyl)-5-fluoro-3-nitropyridin-2-yl)methanol
  • 4,5-Difluoro-2-iodopyridine
  • 3-(Difluoromethyl)-4,5-difluoropicolinamide
  • 4-(Aminomethyl)-5-(difluoromethyl)-6-(trifluoromethoxy)picolinamide
  • 4-(Difluoromethyl)-6-hydroxy-3-(trifluoromethoxy)picolinaldehyde
  • 4-(Difluoromethyl)-6-iodo-2-methoxy-3-nitropyridine
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