4-methoxypyrimidin-2-amine

Names

[ CAS No. ]:
155-90-8

[ Name ]:
4-methoxypyrimidin-2-amine

[Synonym ]:
4-methoxypyrimidin-2-amine

Chemical & Physical Properties

[ Density]:
1.224g/cm3

[ Boiling Point ]:
313.1ºC at 760 mmHg

[ Molecular Formula ]:
C₅H₇N₃O

[ Molecular Weight ]:
125.12900

[ Flash Point ]:
143.2ºC

[ Exact Mass ]:
125.05900

[ PSA ]:
61.03000

[ LogP ]:
0.64860

[ Vapour Pressure ]:
0.000506mmHg at 25°C

[ Index of Refraction ]:
1.566

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UV6475000

CHEMICAL NAME :: Pyrimidine, 2-amino-4-methoxy-

CAS REGISTRY NUMBER :: 155-90-8

BEILSTEIN REFERENCE NO. :: 0118987

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C5-H7-N3-O

MOLECULAR WEIGHT :: 125.15

WISWESSER LINE NOTATION :: T6N CNJ BZ DO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 125 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 6,375,1954

Safety Information

[ HS Code ]:
2933599090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

4-Chloro-6-methoxypyrimidin-2-amine
5-Bromo-4-methoxypyrimidin-2-amine
Bis(pinacolato)diboron
Methanol
2-Amino-4-chloropyrimidine
Sodium Methylate
2,4-Dichloropyrimidine
2,4-Dichloro-6-methoxypyrimidine
2-Amino-5-bromo-4,6-dichloropyrimidine

DownStream

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%