4-Hydroxyphenylacetic acid

Suppliers

Names

[ CAS No. ]:
156-38-7

[ Name ]:
4-Hydroxyphenylacetic acid

[Synonym ]:
4-Hydroxyphenyl acetic acid
2-(4-Hydroxyphenyl)acetic acid
4-hydroxyphenylacetic acid
(p-hydroxyphenyl)-Acetic acid
(4-Hydroxy-phenyl)-acetic acid
4-Hydroxy-Benzeneacetic acid
(4-Hydroxyphenyl)acetic acid
MFCD00004347
Benzeneacetic acid, 4-hydroxy-
EINECS 205-851-3
PHPA

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
346.6±17.0 °C at 760 mmHg

[ Melting Point ]:
148-151 °C(lit.)

[ Molecular Formula ]:
C8H8O3

[ Molecular Weight ]:
152.147

[ Flash Point ]:
177.6±17.4 °C

[ Exact Mass ]:
152.047348

[ PSA ]:
57.53000

[ LogP ]:
0.77

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.596

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AI2680000
CHEMICAL NAME :
Acetic acid, (p-hydroxyphenyl)-
CAS REGISTRY NUMBER :
156-38-7
BEILSTEIN REFERENCE NO. :
1448766
LAST UPDATED :
199803
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C8-H8-O3
MOLECULAR WEIGHT :
152.16
WISWESSER LINE NOTATION :
QV1R DQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 13,286,1958

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
AI2680000

[ HS Code ]:
2918290000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-Hydroxyphenyl ethanol
  • 4-Methoxyphenylacetic acid
  • 4-Hydroxyphenylacetonitrile
  • BENZYL 2-(4-(BENZYLOXY)PHENYL)ACETATE
  • Methyl 4-chlorophenylacetate
  • p-hydroxyphenylacetamide
  • 4-[2-(bromomethyl)-1,3-dioxolan-2-yl]phenol
  • DL-Phenylalanine
  • Methyl 4-Hydroxyphenylacetate
  • 2-Bromo-4'-hydroxyacetophenone

DownStream

  • 2-hydroxy-5-(2-hydroxyethyl)benzaldehyde
  • Isoxepac
  • Coelenterazine
  • 3-Chloro-4-hydroxyphenylacetic acid
  • Methyl (4-cyanophenyl)acetate
  • pterostilbene
  • ethyl 4-ethoxyphenylacetate
  • 2-(4-butoxyphenyl)acetamide
  • (R)-(+)-Atenolol

Customs

[ HS Code ]: 2918290000

[ Summary ]:
HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

Articles

HMDB: a knowledgebase for the human metabolome.

Nucleic Acids Res. 37(Database issue) , D603-10, (2009)

The Human Metabolome Database (HMDB, http://www.hmdb.ca) is a richly annotated resource that is designed to address the broad needs of biochemists, clinical chemists, physicians, medical geneticists, ...

Age-related reference values for urinary organic acids in a healthy Turkish pediatric population.

Clin. Chem. 40(6) , 862-6, (1994)

Organic acid concentrations were quantified by gas chromatography and the individual acids identified by mass spectrometry in urine specimens from a healthy Turkish pediatric population of ages 2 days...

Prediction of skeletal muscle and fat mass in patients with advanced cancer using a metabolomic approach.

J. Nutr. 142(1) , 14-21, (2012)

Urine and plasma metabolites originate from endogenous metabolic pathways in different organs and exogenous sources (diet). Urine and plasma were obtained from advanced cancer patients and investigate...


More Articles

Related Compounds

  • ETHYL-4-HYDROXYPHENYLACETIC ACID
  • 3-Bromo-4-hydroxyphenylacetic acid
  • 2-BROMO-4-HYDROXYPHENYLACETIC ACID
  • 3-ethoxy-4-hydroxyphenylacetic acid
  • 2-methyl-4-hydroxyphenylacetic acid
  • 3-Fluoro-4-hydroxyphenylacetic acid
  • 1-(Furan-2-yl)piperazin-2-one
  • Methyl 2-[(4-hydroxyphenyl)methyl]pyrrolidine-2-carboxylate
  • (2-Benzylpiperidin-2-yl)methanol
  • Methyl 3-(1,2,3,4-tetrahydroisoquinolin-4-yl)propanoate
  • 5-Amino-3-(1-methyl-2-indolyl)isoxazole
  • 2-[3-Chloro-5-(trifluoromethyl)phenyl]morpholine
  • tert-butyl N-[2-(5-amino-1,2-oxazol-3-yl)phenyl]carbamate
  • 2-(3-aminopropyl)-5-fluoro-N,N-dimethylaniline
  • 2-[2-(Dimethylamino)-4-fluorophenyl]propanoic acid
  • 5-(Aminomethyl)-1-(3-methoxypropyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione