Cysteamine Hydrochloride

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Names

[ CAS No. ]:
156-57-0

[ Name ]:
Cysteamine Hydrochloride

[Synonym ]:
2-AMino&CYSTEAMINE HCL
1-Amino-2-mercaptoethane hydrochloride
2-aminoethylmercaptan hydrochloride
2-Mercapto ethyl amine hydrochloride
EINECS 205-858-1
β-Mercapto ethylamine hydrochloride
CYSTEAMINE HCL SOLID
Cysteinamine Hydrochloride
thiol hydrochloride
2-Mercaptoethylamine hydrochloride
Cysteamine Hydrochloride
2-Aminoethanethiol hydrochloride (1:1)
Cysteamine (Hydrochloride)
2-Aminoethanethiol Hydrochloride
Thioethanolamine hydrochloride
2-Mercaptoethanamine Hydrochloride
CYSTEAMINIUM CHLORIDE
2-Mercaptoethylamin
2-amino-ethanethiol hydrochloride
1-Aminoethane-2-thiol hydrochloride
Cysteamine HCl
mea hydrochloride
b-Mercaptoethylamine Hydrochloride
2-Amino-ethanethiol.HCl
Ethanethiol, 2-amino-, hydrochloride (1:1)
β-Mercaptoethylamine hydrochloride
MFCD00012904
Decarboxycysteine hydrochloride
2-Amino-ethanethiol;hydrochloride
2-Mercaptoethylammonium chloride
Aminoethanethiol hydrochloride

Chemical & Physical Properties

[ Density]:
0.75

[ Boiling Point ]:
116.4ºC at 760 mmHg

[ Melting Point ]:
67-71 °C

[ Molecular Formula ]:
C2H8ClNS

[ Molecular Weight ]:
113.610

[ Flash Point ]:
24.2ºC

[ Exact Mass ]:
113.006599

[ PSA ]:
64.82000

[ LogP ]:
1.37720

[ Vapour Pressure ]:
16.7mmHg at 25°C

[ Storage condition ]:
2-8°C

[ Stability ]:
Stable, but hygroscopic. Incompatible with strong oxidizing agents.

[ Water Solubility ]:
VERY SOLUBLE

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KJ0200000
CHEMICAL NAME :
Ethanethiol, 2-amino-, hydrochloride
CAS REGISTRY NUMBER :
156-57-0
LAST UPDATED :
199701
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C2-H7-N-S.Cl-H
MOLECULAR WEIGHT :
113.62
WISWESSER LINE NOTATION :
Z2SH &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1352 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
900 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
244 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
Micronucleus test

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Rodent - rat Liver
DOSE/DURATION :
5 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 153,57,1985

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S36/37/39-S26

[ RIDADR ]:
UN 3335

[ WGK Germany ]:
3

[ RTECS ]:
KJ0200000

[ HS Code ]:
2921199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-mercapto thiazoline
  • Aziridine
  • Nitrogen
  • 2-Butanone
  • L-alanine
  • 2-Chloroethanamine hydrochloride
  • 2-Mercapto-1,3-thiazole
  • 2-(2-Mercaptoethyl)isoindoline-1,3-dione
  • hydrochloride salt of (1-chloro-2-acetylamino-2-methyl-1-phenylpropyl) 2-aminoethyl sulfide

DownStream

  • 2-[(3-chlorobenzyl)thio]ethanamine(SALTDATA: FREE)
  • 2-[(4-METHYLBENZYL)THIO]ETHANAMINE
  • 2-(3-phenylquinolin-2-yl)sulfanylethanamine
  • [2-(Pyridin-2-ylthio)ethyl]amine dihydrochloride
  • 2-phenylthiazolidine
  • 2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethylamine dihydrochloride
  • Thiazolidine,2-(4-methoxyphenyl)-
  • N,S-Diacetylcysteamine
  • 2-[(4-Fluorobenzyl)sulfanyl]ethanamine
  • 2-[(2,6-dichlorophenyl)methylsulfanyl]ethanamine

Customs

[ HS Code ]: 2930909090

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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Related Compounds

  • Cysteamine Hydrochloride
  • S-benzyl-cysteamine hydrochloride
  • cysteamine hydrochloride, [1,2-14c]
  • S-2-Pyridylthio Cysteamine Hydrochloride
  • Cysteamine sulfate
  • 2-aminoethanethiol,hydrochloride
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • N-(3-chloro-4-methylphenyl)-1-(4-fluorophenyl)-3-methyl-4-oxo-4,7-dihydro-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • (5-Bromo-3-chloro-2-methoxyphenyl)(methyl)sulfane