Alvimopan

Suppliers

Names

[ CAS No. ]:
156053-89-3

[ Name ]:
Alvimopan

[Synonym ]:
Alvimopan
N-{(2S)-2-benzyl-3-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]propanoyl}glycine
Glycine, N-[(2S)-3-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]-1-oxo-2-(phenylmethyl)propyl]-
N-{(2S)-2-Benzyl-3-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]propanoyl}glycine
Unii-Q153V49p3z

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
684.1±55.0 °C at 760 mmHg

[ Melting Point ]:
210-213ºC

[ Molecular Formula ]:
C25H32N2O4

[ Molecular Weight ]:
424.533

[ Flash Point ]:
367.5±31.5 °C

[ Exact Mass ]:
424.236206

[ PSA ]:
89.87000

[ LogP ]:
3.38

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.572

[ Storage condition ]:
2-8°C

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H400

[ Precautionary Statements ]:
P273-P280-P305 + P351 + P338-P337 + P313-P391

[ RIDADR ]:
UN 3077 9 / PGIII

[ HS Code ]:
2933399090

Synthetic Route

Precursor & DownStream

Precursor

  • ethyl 2-benzylacrylate
  • (+)-(3R,4R)-3,4-DIMETHYL-4-(3-HYDROXYPHENYL)PIPERIDINE
  • Benzenepropanoic acid, a-(hydroxyMethyl)-, (S)-

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds

  • Alvimopan
  • ALVIMOPAN
  • Alvimopan-d5
  • Alvimopan monohydrate
  • Alvimopan metabolite-d5
  • Alvimopan Intermediate 1