2-ethylhexyl diphenyl phosphite

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Names

[ Name ]:
2-ethylhexyl diphenyl phosphite

[Synonym ]:
diphenyl(2-ethylhexyl)phosphite
Phosphorous acid diphenyl 2-ethylhexyl ester
2-ethylhexyl diphenyl ester
forstabk201
Phosphorigsaeure-(2-aethyl-hexylester)-diphenylester
phosphorous acid-(2-ethyl-hexyl ester)-diphenyl ester
Phosphorousacid,2-ethylhexyldiphenylester
O,O-Diphenyl-O-(2-ethylhexyl)phosphite
forstab
Einecs 239-716-5
MFCD00071517
diphenyl ethylhexyl phosphite

Chemical & Physical Properties

[ Boiling Point ]:
389.9ºC at 760mmHg

[ Melting Point ]:
215-219 °C(lit.)

[ Molecular Formula ]:
C₂₀H₂₇O₃P

[ Molecular Weight ]:
346.40000

[ Flash Point ]:
234.1ºC

[ Exact Mass ]:
346.17000

[ PSA ]:
41.28000

[ LogP ]:
6.60430

[ Vapour Pressure ]:
6.21E-06mmHg at 25°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TG8800000

CHEMICAL NAME :: Phosphorous acid, 2-ethylhexyl diphenyl ester

CAS REGISTRY NUMBER :: 15647-08-2

BEILSTEIN REFERENCE NO. :: 2297250

LAST UPDATED :: 199701

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C20-H27-O3-P

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1880 mg/kg

TOXIC EFFECTS :: Autonomic Nervous System - other (direct) parasympathomimetic Peripheral Nerve and Sensation - structural change in nerve or sheath Behavioral - tremor

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 23(1),41,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2150 mg/kg

TOXIC EFFECTS :: Autonomic Nervous System - other (direct) parasympathomimetic Peripheral Nerve and Sensation - structural change in nerve or sheath Behavioral - tremor

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 23(1),41,1979

TYPE OF TEST :: LC - Lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: >2500 ug/m3/2H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 23(1),41,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Autonomic Nervous System - other (direct) parasympathomimetic Peripheral Nerve and Sensation - structural change in nerve or sheath Behavioral - tremor

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 23(1),41,1979 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5 mg/m3/4H/22W-I

TOXIC EFFECTS :: Blood - changes in erythrocyte (RBC) count Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase Biochemical - Metabolism (Intermediary) - xanthine, purine or nucleotides including urate

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 23(1),41,1979

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 3600 mg/kg/45D-I

TOXIC EFFECTS :: Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 23(1),41,1979

Safety Information

[ Hazard Codes ]:
Xn,Xi

[ Risk Phrases ]:
R22:Harmful if swallowed. R36/37/38:Irritating to eyes, respiratory system and skin . R43:May cause sensitization by skin contact.

[ Safety Phrases ]:
S26-S36/37

[ WGK Germany ]:
3

[ HS Code ]:
2920901900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

2-Ethylhexanol
Diphenyl phosphorochloridite

DownStream

Customs

[ HS Code ]: 2920901900

[ Summary ]:
2920901900 VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Related Compounds

di-2-ethylhexyl phosphite
Tris(2-ethylhexyl) phosphite-dibromomercury (1:1)
phosphorus-32
UNII:J9H3L1N82V
cadmium bis(2-ethylhexyl) phosphite
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