7-Diethylamino-3-[N-(2-maleimidoethyl)carbamoyl]coumarin

Names

[ CAS No. ]:
156571-46-9

[ Name ]:
7-Diethylamino-3-[N-(2-maleimidoethyl)carbamoyl]coumarin

[Synonym ]:
7-(diethylamino)-N-[2-(2,5-dioxopyrrol-1-yl)ethyl]-2-oxochromene-3-carboxamide

Chemical & Physical Properties

[ Density]:
1.346g/cm3

[ Boiling Point ]:
690.5ºC at 760mmHg

[ Molecular Formula ]:
C₂₀H₂₁N₃O₅

[ Molecular Weight ]:
383.39800

[ Flash Point ]:
371.4ºC

[ Exact Mass ]:
383.14800

[ PSA ]:
99.93000

[ LogP ]:
1.62280

[ Vapour Pressure ]:
6.42E-19mmHg at 25°C

[ Index of Refraction ]:
1.624

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R22

[ RIDADR ]:
NONH for all modes of transport

Articles

A fluorescent sensor of the phosphorylation state of nucleoside diphosphate kinase and its use to monitor nucleoside diphosphate concentrations in real time.

Biochemistry 40(16) , 5087-94, (2001)

A sensor for purine nucleoside diphosphates in solution based on nucleoside diphosphate kinase (NDPK) has been developed. A single cysteine was introduced into the protein and labeled with the environ...

A new method for the time-resolved measurement of phosphate release in permeabilized muscle fibers.

Biophys. J. 68(4 Suppl) , 191S-192S; discussion 192S-193S, (1995)

A new method for the measurement of phosphate release in contracting and relaxed permeabilized muscle fibers is described. The assay is based on a genetically engineered phosphate-binding protein labe...

Development of fluorescent biosensors for probing the function of motor proteins.

Mol. Biosyst. 3(4) , 249-56, (2007)

Biosensors are becoming widely used both in basic research and in screening assays and reagentless sensors with fluorescent reporter groups attached to proteins form one class. This article describes ...