SNC80

Suppliers

Names

[ Name ]:
SNC80

[Synonym ]:
(+)-4-[(αR)-α-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide
4-[(R)-[(2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl](3-methoxyphenyl)methyl]-N,N-diethylbenzamide
SNC80
Benzamide, 4-[(R)-[(2S,5R)-2,5-dimethyl-4-(2-propen-1-yl)-1-piperazinyl](3-methoxyphenyl)methyl]-N,N-diethyl-
4-[(R)-[(2S,5R)-4-Allyl-2,5-dimethylpiperazin-1-yl](3-methoxyphenyl)methyl]-N,N-diethylbenzamide
MFCD00672673
2-Pyridylethylamine dihydrochloride

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
564.8±50.0 °C at 760 mmHg

[ Melting Point ]:
122-123ºC

[ Molecular Formula ]:
C₂₈H₃₉N₃O₂

[ Molecular Weight ]:
449.628

[ Flash Point ]:
295.4±30.1 °C

[ Exact Mass ]:
449.304230

[ PSA ]:
36.02000

[ LogP ]:
3.37

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.545

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

N,N-diethyl-4-formylbenzamide
3-Methoxyphenylmagnesium bromide solution
Piperazine, 2,5-dimethyl-1-(2-propenyl)-, (2R,5S)- (9CI)
RAC-4-(3'-METHOXY-A-CHLOROBENZYL)-N,N-DIETHYLBENZAMIDE
(3-methoxyphenyl)-(4-methylphenyl)methanone
4-(3-Methoxybenzoyl)benzoic acid
(2R,5S)-2,5-Dimethylpiperazine
4-Formylbenzoic acid
3-Methoxybenzoyl chloride

DownStream

Articles

PKA and ERK1/2 are involved in dopamine D₁ receptor-induced heterologous desensitization of the δ opioid receptor.

Life Sci. 92(23) , 1101-9, (2013)

Chronic administration of cocaine attenuates delta opioid receptor (DOPR) signaling in the striatum and the desensitization is mediated by the indirect actions of cocaine on dopamine D1 receptors (D1R...

Novel screening assay for the selective detection of G-protein-coupled receptor heteromer signaling.

J. Pharmacol. Exp. Ther. 344(1) , 179-88, (2013)

Drugs targeting G-protein-coupled receptors (GPCRs) make up more than 25% of all prescribed medicines. The ability of GPCRs to form heteromers with unique signaling properties suggests an entirely new...

Dual efficacy of delta opioid receptor-selective ligands for ethanol drinking and anxiety.

J. Pharmacol. Exp. Ther. 335(1) , 133-9, (2010)

Alcoholism and anxiety disorders have a huge impact on society and afflict 17.6 million and 40 million people in the United States, respectively. A strong comorbidity exists between alcoholism and anx...

(Rac)-SNC80
benzyl N-[4-(1-chlorocyclopropyl)pyrimidin-2-yl]carbamate
Ethyl 3,4-dihydro-8-methoxy-2H-1-benzopyran-4-carboxylate
rac-(1R,5R,6S)-6-acetamidobicyclo[3.2.0]heptane-3-carboxylic acid
2-Acetamido-3-(1,3-oxazol-4-yl)propanoic acid
3-(3-acetamido-1H-1,2,4-triazol-1-yl)propanoic acid
3,5-dimethyl-4-[(N-methylacetamido)methyl]benzoic acid
3-(Ethylamino)-1-(1-hydroxy-2-naphthalenyl)-2-buten-1-one
2-Benzofuranol, 5-chloro-2,3-dihydro-3-(trifluoromethyl)-
2,6-Bis(propan-2-yl)imidazo[2,1-b][1,3]thiazole-5-carboxylic acid
N2-Butyl-N4,N6-dicyclohexyl-1,3,5-triazine-2,4,6-triamine