2-Hydroxy-4-quinolincarboxylic acid

Suppliers

Names

[ CAS No. ]:
15733-89-8

[ Name ]:
2-Hydroxy-4-quinolincarboxylic acid

[Synonym ]:
2-Hydroxy-quinoline-4-carboxylic acid
2-oxo-1H-quinoline-4-carboxylic acid
4-Quinolinecarboxylic acid, 1,2-dihydro-2-oxo-
MFCD00023942
2-oxo-1,2-dihydroquinoline-4-carboxylic acid
EINECS 239-827-9
2-Hydroxy-4-quinolincarboxylic acid
2-Oxo-1,2-dihydro-4-quinolinecarboxylic acid
2-Hydroxycinchoninic acid
2-Hydroxyquinoline-4-carboxylic acid
1,2-Dihydro-2-oxoquinoline-4-carboxylic acid
4-Quinolinecarboxylic acid, 2-hydroxy-

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
473.6±30.0 °C at 760 mmHg

[ Melting Point ]:
>300ºC

[ Molecular Formula ]:
C10H7NO3

[ Molecular Weight ]:
189.167

[ Flash Point ]:
240.2±24.6 °C

[ Exact Mass ]:
189.042587

[ PSA ]:
70.42000

[ LogP ]:
2.19

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.730

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GD3869000
CHEMICAL NAME :
Cinchoninic acid, 2-hydroxy-
CAS REGISTRY NUMBER :
15733-89-8
LAST UPDATED :
199603
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C10-H7-N-O3
MOLECULAR WEIGHT :
189.18

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 5,338,1953

Safety Information

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S26-S36

[ RTECS ]:
GD3869000

[ HS Code ]:
2933499090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Malonic acid
  • isatin
  • 1-Acetyl-1H-indole-2,3-dione
  • 2-Chloro-4-quinolinecarboxylic acid
  • ETHYL 2-OXO-3-INDOLINEGLYOXYLATE
  • hydroxy-(2-oxo-indolin-3-yl)-acetic acid ethyl ester
  • N-acetylisatic acid
  • lepidine
  • Ethyl 2-chloroquinoline-4-carboxylate

DownStream

  • 1-methyl-2-oxo-3,4-dihydroquinoline-4-carboxylic acid
  • 4-Quinolinecarboxylic acid
  • 2-CHLORO-N-[2-(DIETHYLAMINO)ETHYL]-4-QUINOLINECARBOXAMIDE
  • 2-Chloroquinolin-4-amine
  • 2-Chloro-4-quinolinecarboxylic acid
  • Methyl 2-chloro-4-quinolinecarboxylate
  • Ethyl 4-quinolinecarboxylate
  • 2-oxo-3,4-dihydro-1H-quinoline-4-carboxylic acid
  • 2-Bromoquinoline-4-carboxylic acid
  • 2-Chloro quinoline-4-chloroformyl

Customs

[ HS Code ]: 2933499090

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 2-Hydroxy-4-quinolincarboxylic acid
  • 2-hydroxy-4-tetradecoxybenzoic acid
  • 2-hydroxy-4-sulfobenzoic acid,dihydrate
  • 2-hydroxy-4-methoxythiobenzoic acid S-methyl ester
  • 2-hydroxy-4-octoxybenzoic acid
  • 2-hydroxy-4-oxohexanoic acid methyl ester
  • Phenyl-(4-quinazolin-4-yl-piperazin-1-yl)-methanone
  • 2-(7-(furan-2-yl)-4-oxo-2-(piperidin-1-yl)thiazolo[4,5-d]pyridazin-5(4H)-yl)-N-isopropyl-N-phenylacetamide
  • methyl {7-[2-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-2-oxoethoxy]-4-methyl-2-oxo-2H-chromen-3-yl}acetate
  • Methyl 1-(4-methoxybenzamido)cyclohexane-1-carboxylate
  • (4-(3-chlorophenyl)piperazin-1-yl)(1-methyl-5-(1H-pyrrol-1-yl)-1H-pyrazol-4-yl)methanone
  • 2-(((3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl)methyl)thio)-3-phenylthieno[3,2-d]pyrimidin-4(3H)-one
  • 2-(ethylsulfanyl)-3-methylthieno[3,2-d]pyrimidin-4(3H)-one
  • 4-iodo-N,N-dimethyl-1H-pyrrole-2-carboxamide
  • Ethyl 6-phenylimidazo[2,1-b][1,3]thiazole-2-carboxylate
  • 5-Chloro-6-cyclopropyl-2-oxo-1,2-dihydro-3-pyridinecarbonitrile
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