(S)-SNAP 5114

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Names

[ CAS No. ]:
157604-55-2

[ Name ]:
(S)-SNAP 5114

[Synonym ]:
HMS3268E15
SNAP-5114
Pseudo RACK1
(S)-SNAP-5114

Chemical & Physical Properties

[ Density]:
1.175g/cm3

[ Boiling Point ]:
643.9ºC at 760mmHg

[ Molecular Formula ]:
C₃₀H₃₅NO₆

[ Molecular Weight ]:
505.60

[ Flash Point ]:
343.2ºC

[ Exact Mass ]:
505.24600

[ PSA ]:
77.46000

[ LogP ]:
4.75540

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.571

[ Storage condition ]:
-20°C

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

Articles

GABA transporter heterogeneity: pharmacology and cellular localization.

Neurochem. Int. 29 , 335, (1996)

gamma-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain. GABA is cleared from the synaptic cleft by specific, high-affinity, sodium- and chloride-dependent trans...

GABA-level increasing and anticonvulsant effects of three different GABA uptake inhibitors.

Neuropharmacology 39 , 2399-2407, (2000)

The present study examines the effect of tiagabine (a selective inhibitor of GABA transporter 1, GAT-1), SNAP-5114 (a semi-selective inhibitor of rat GAT-3/mouse GAT4) and NNC 05-2045 (a non-selective...

GABAergic signaling is linked to a hypermigratory phenotype in dendritic cells infected by Toxoplasma gondii.

PLoS Pathog. 8 , e1003051, (2012)

During acute infection in human and animal hosts, the obligate intracellular protozoan Toxoplasma gondii infects a variety of cell types, including leukocytes. Poised to respond to invading pathogens,...

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