bis(4-methylphenyl) ether

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Names

[ CAS No. ]:
1579-40-4

[ Name ]:
bis(4-methylphenyl) ether

[Synonym ]:
MFCD00025979
EINECS 216-423-0
4,4'-Oxybis(methylbenzene)
4-Tolyl Ether
1,1'-Oxybis(4-methylbenzene)
1-methyl-4-(4-methylphenoxy)benzene
Benzene, 1,1'-oxybis[4-methyl-
bis(4-methylphenyl) ether
4,4'-Dimethyldiphenyl Ether
Di-p-tolyl Ether

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
285.5±9.0 °C at 760 mmHg

[ Melting Point ]:
47-49 °C(lit.)

[ Molecular Formula ]:
C14H14O

[ Molecular Weight ]:
198.260

[ Flash Point ]:
121.3±14.4 °C

[ Exact Mass ]:
198.104462

[ PSA ]:
9.23000

[ LogP ]:
5.13

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.561

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DA6625000
CHEMICAL NAME :
Benzene, 1,1'-oxybis(4-methyl-
CAS REGISTRY NUMBER :
1579-40-4
LAST UPDATED :
199710
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C14-H14-O
MOLECULAR WEIGHT :
198.28

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0545443 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2250 mg/kg
TOXIC EFFECTS :
Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0537676
TYPE OF TEST :
LC - Lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>184 ppm/4H
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - respiratory stimulation Blood - other changes
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0537676
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
7940 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - other changes Blood - hemorrhage
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0545443

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335-H410

[ Precautionary Statements ]:
P261-P273-P305 + P351 + P338-P501

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;N: Dangerous for the environment;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S61

[ RIDADR ]:
UN 3077 9/PG 3

[ WGK Germany ]:
2

[ RTECS ]:
DA6625000

[ HS Code ]:
2902909090

Synthetic Route

Precursor & DownStream

Precursor

  • p-Cresol
  • 4-Iodotoluene
  • 4-Bromotoluene
  • 4-Chlorotoluene
  • 4-Tolylboronic acid
  • tert-butyl-dimethyl-(4-methylphenoxy)silane
  • Benzene,1-methoxy-2-phenoxy-
  • sodium p-cresolate
  • Sulfonium, tris(4-methylphenyl)-, bromide

DownStream

  • 2,4,6-Trichloropyrimidine
  • 4-(P-TOLYLOXY)BENZONITRILE
  • Bis[4-(bromomethyl)phenyl] ether
  • 2,8-dimethylphenoxathiine
  • Benzene,1,1'-oxybis[4-(chloromethyl)-
  • 4-Methylcyclohexanol
  • Toluene
  • 2,6-Dinitro-p-cresol
  • bis-(4-methyl-2-nitro-phenyl)-ether
  • 4-Methyl-2-nitrophenol

Customs

[ HS Code ]: 2902909090

[ Summary ]:
2902909090 other aromatic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%

Articles

Spontaneous Generation of Chirality in Simple Diaryl Ethers.

Chirality 27 , 425-9, (2015)

We studied the spontaneous formation of chiral crystals of four diaryl ethers, 3-phenoxybenzaldehyde, 1; 1,3-dimethyl-2-phenoxybenzene, 2; di(4-aminophenyl) ether, 3; and di(p-tolyl) ether, 4. Compoun...

Solid-State 13C NMR, X-ray, and Quantum Mechanical Studies of the Carbon Chemical Shifts Tensors of p-Tolyl Ether. Facelli JC, et al.

J. Phys. Chem. 98(47) , 12186-90, (1994)

XII.-Substituted diaryl ethers. Part I. Di-p-tolyl ether. BoydáBarrett HS.

J. Chem. Soc. , 67-73, (1927)


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  • bis(4-methylphenyl) butanedioate
  • bis(4-methylphenyl)-(2-phenylethynyl)phosphane
  • BIS-(4-METHYLPHENYL) MALONATE
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  • bis(4-methylphenyl)-bis(prop-2-enyl)silane
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