H-Cys-Val-2-Nal-Met-OH

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Names

[ CAS No. ]:
158022-12-9

[ Name ]:
H-Cys-Val-2-Nal-Met-OH

[Synonym ]:
Cys-Val-2-Nal-Met

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₆H₃₆N₄O₅S₂

[ Molecular Weight ]:
548.71800

[ Exact Mass ]:
548.21300

[ PSA ]:
214.72000

[ LogP ]:
3.46050

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Nonfarnesylated tetrapeptide inhibitors of protein farnesyltransferase.

J. Biol. Chem. 266 , 15575-15578, (1991)

The protein farnesyltransferase from rat brain was previously shown to be inhibited competitively by tetrapeptides that conform to the consensus Cys-A1-A2-X, where A1 and A2 are aliphatic amino acids ...

Infectious tolerance via the consumption of essential amino acids and mTOR signaling.

Proc. Natl. Acad. Sci. U. S. A. 106 , 12055-60, (2009)

Infectious tolerance describes the process of CD4(+) regulatory T cells (Tregs) converting naïve T cells to become additional Tregs. We show that antigen-specific Tregs induce, within skin grafts and ...

Hamilton, A.D. and Sebti, S.M

Drug News Perspect. 8 , 138, (1995)

(H-CYS-VAL-OH)2
(H-Cys-Val-OH)2(Disulfide bond)
FTase Inhibitor II
3-Naphth-2-yl-L-alanine
D-Cystine
Benzenecarboximidothioic acid, N-hydroxy-4-methyl-, 2-(diethylamino)et hyl ester, monohydrochloride, (Z)-
2-[4-(5-Ethyl-6-methylpyrimidin-4-yl)piperazin-1-yl]quinoxaline
3-(3-Fluorophenyl)-6-[4-(2-methylpyrimidin-4-yl)piperazin-1-yl]pyridazine
3-(3-Fluorophenyl)-6-[4-(4-methylpyrimidin-2-yl)piperazin-1-yl]pyridazine
4-fluoro-2-[2-(1-methyl-1H-pyrazol-4-yl)piperidin-1-yl]-1,3-benzothiazole
2-{4-[(5-Fluoropyrimidin-2-yl)oxy]piperidin-1-yl}quinoline
2-[4-(5-Ethyl-6-methylpyrimidin-4-yl)piperazin-1-yl]-6-fluoro-1,3-benzoxazole
3-(4-Fluorophenyl)-6-{4-[(5-methyl-1,3-oxazol-4-yl)methyl]piperazin-1-yl}pyridazine
6-methoxy-N-(1-{thieno[3,2-d]pyrimidin-4-yl}azetidin-3-yl)pyridine-3-carboxamide
3-(4-Methylphenyl)-6-[4-(2-methylpyrimidin-4-yl)piperazin-1-yl]pyridazine
4-({4-[6-(3-Fluorophenyl)pyridazin-3-yl]piperazin-1-yl}methyl)-1-methyl-1,2-dihydropyridin-2-one

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