H-Cys-Val-2-Nal-Met-OH

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Names

[ CAS No. ]:
158022-12-9

[ Name ]:
H-Cys-Val-2-Nal-Met-OH

[Synonym ]:
Cys-Val-2-Nal-Met

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₆H₃₆N₄O₅S₂

[ Molecular Weight ]:
548.71800

[ Exact Mass ]:
548.21300

[ PSA ]:
214.72000

[ LogP ]:
3.46050

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Nonfarnesylated tetrapeptide inhibitors of protein farnesyltransferase.

J. Biol. Chem. 266 , 15575-15578, (1991)

The protein farnesyltransferase from rat brain was previously shown to be inhibited competitively by tetrapeptides that conform to the consensus Cys-A1-A2-X, where A1 and A2 are aliphatic amino acids ...

Infectious tolerance via the consumption of essential amino acids and mTOR signaling.

Proc. Natl. Acad. Sci. U. S. A. 106 , 12055-60, (2009)

Infectious tolerance describes the process of CD4(+) regulatory T cells (Tregs) converting naïve T cells to become additional Tregs. We show that antigen-specific Tregs induce, within skin grafts and ...

Hamilton, A.D. and Sebti, S.M

Drug News Perspect. 8 , 138, (1995)

(H-CYS-VAL-OH)2
(H-Cys-Val-OH)2(Disulfide bond)
FTase Inhibitor II
3-Naphth-2-yl-L-alanine
D-Cystine
Benzenecarboximidothioic acid, N-hydroxy-4-methyl-, 2-(diethylamino)et hyl ester, monohydrochloride, (Z)-
9-Azabicyclo[3.3.1]nonan-3-amine, 9-(2-ethoxyethyl)-N-methyl-
5-Bromo-2-(2-tert-butylphenoxy)pyridine
9-(Thiophen-2-ylmethyl)-9-azabicyclo[3.3.1]nonan-3-amine
N-((2-(tetrahydro-2H-pyran-4-yl)cyclopropyl)methyl)cyclopropanamine
9-Azabicyclo[3.3.1]nonan-3-amine, 9-(3-methylbutyl)-
4-Bromo-1-(2,4-dimethylphenoxy)-2-nitrobenzene
N-[(2,2-dimethylcyclopropyl)methyl]cyclopropanamine
9-Acridinecarboxylic acid, 7-bromo-1,2,3,4-tetrahydro-4,5-dimethyl-
2-(4-(Trifluoromethyl)phenyl)-4,5,6,7-tetrahydrooxazolo[4,5-C]pyridine
1-(Tetrahydro-3-furanyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2(1h)-pyridinone

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