SR 141716A

Suppliers

Names

[ CAS No. ]:
158681-13-1

[ Name ]:
SR 141716A

[Synonym ]:
5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(1-piperidinyl)-1H-pyrazole-3-carboxamide hydrochloride (1:1)
5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide hydrochloride (1:1)
1H-Pyrazole-3-carboxamide, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-, hydrochloride (1:1)
Rimonabant hydrochloride
5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidin-1-ylpyrazole-3-carboxamide,hydrochloride
MFCD04034714
Rimonabant (Hydrochloride)

Chemical & Physical Properties

[ Boiling Point ]:
627.6ºC at 760 mmHg

[ Melting Point ]:
230-240ºC

[ Molecular Formula ]:
C22H22Cl4N4O

[ Molecular Weight ]:
500.248

[ Flash Point ]:
333.3ºC

[ Exact Mass ]:
498.054779

[ PSA ]:
50.16000

[ LogP ]:
7.06940

[ Storage condition ]:
-20°C Freezer

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H319

[ Precautionary Statements ]:
P301 + P310-P305 + P351 + P338

[ Hazard Codes ]:
T,Xi

[ Risk Phrases ]:
25-36

[ Safety Phrases ]:
26-45

[ RIDADR ]:
UN 2811 6.1 / PGIII

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-Piperidinamine
  • 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-pyrazole-3-carboxylic acid chloride
  • Rimonabant
  • 4'-Chloropropiophenone
  • 1-(2,4-dichlorophenyl)hydrazine hydrochloride

DownStream

  • Rimonabant

Articles

Obesity drug therapy.

Minerva Endocrinol. 38(3) , 245-54, (2013)

Obesity is a chronic disease, and it requires chronic therapy. Hypertension, dyslipidemia, diabetes and cardiovascular diseases are leading causes of mortality in the modern world. All of them are str...

Anandamide-CB1 receptor signaling contributes to postnatal ethanol-induced neonatal neurodegeneration, adult synaptic, and memory deficits.

J. Neurosci. 33(15) , 6350-66, (2013)

The transient exposure of immature rodents to ethanol during postnatal day 7 (P7), which is comparable with the third trimester in human pregnancy, induces synaptic dysfunctions. However, the molecula...

Reduced food intake is the major contributor to the protective effect of rimonabant on islet in established obesity-associated type 2 diabetes.

Yonsei Med. J. 54(5) , 1127-36, (2013)

Although the presence of cannabinoid type 1 (CB1) receptor in islets has been reported, the major contributor to the protective effect of rimonabant on islet morphology is unknown. We determined wheth...


More Articles

Related Compounds

  • Rimonabant
  • SR 16832
  • SR 3677 dihydrochloride
  • SR-1277
  • SR 0987
  • SR 11302
  • (S)-11-Chloro-4-ethyl-10-nitro-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl acetate
  • N-Ethyl-I+/--methyl-5-(1-methylethyl)-1,3,4-oxadiazole-2-methanamine
  • Thieno[3,2-f]benzofuran
  • 4(1H)-Pyrimidinone, 2,3-dihydro-2-thioxo-1-(3,3,3-trifluoropropyl)-
  • (2-Aminoethyl)(3,3,3-trifluoropropyl)amine
  • Butanimidamide, 2-[(5-chloro-3-pyridinyl)oxy]-
  • 3-(3-Chloropropanoyl)-1-(3,3,3-trifluoropropyl)urea
  • 3-(3-Chloropyridin-4-yl)-1,1,1-trifluoropropan-2-one
  • O-(4-Chlorophenyl)-D-serine
  • 3-(Chloromethyl)-4-methyl-1,2-oxazole
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.