3,4-dimethyl-6h-isoxazolo[3,4-d]pyridazin-7-one

Names

[ CAS No. ]:
15911-16-7

[ Name ]:
3,4-dimethyl-6h-isoxazolo[3,4-d]pyridazin-7-one

[Synonym ]:
Isoxazolo[3,4-d]pyridazin-7(6H)-one,3,4-dimethyl-(8CI,9CI)
6,7-Dimethyl-isoxazolo<3,4-d>pyridazin-7-on
4-d)pyridazin-7(6h)-one,3,4-dimethyl-isoxazolo(
3,4-Dimethylisoxazolo<3,4-d>pyridazin-7-on
3,4-DIMETHYLISOXAZOLO[3,4-D]PYRIDAZIN-7(6H)-ONE

Chemical & Physical Properties

[ Density]:
1.58g/cm3

[ Molecular Formula ]:
C7H7N3O2

[ Molecular Weight ]:
165.14900

[ Exact Mass ]:
165.05400

[ PSA ]:
71.78000

[ LogP ]:
0.52790

[ Index of Refraction ]:
1.709

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NY3360000
CHEMICAL NAME :
Isoxazolo(3,4-d)pyridazin-7(6H)-one, 3,4-dimethyl-
CAS REGISTRY NUMBER :
15911-16-7
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C7-H7-N3-O2
MOLECULAR WEIGHT :
165.17
WISWESSER LINE NOTATION :
T56 BNO GNMVJ D1 F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 24,885,1969

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Ethyl 4-acetyl-5-methylisoxazole-3-carboxylate
  • 2,4-Pentandione

DownStream

  • 5-ACETYL-4-AMINO-6-METHYL-2H-PYRIDAZIN-3-ONE

Related Compounds

  • 6-{3-[4-(3-Chloro-phenyl)-piperazin-1-yl]-propyl}-3,4-dimethyl-6H-isoxazolo[3,4-d]pyridazin-7-one
  • BUTTPARK 110\40-76
  • 6-[2-(diethylamino)ethyl]-3,4-dimethyl-[1,2]oxazolo[3,4-d]pyridazin-7-one
  • 6-[2-(dimethylamino)ethyl]-3,4-dimethyl-[1,2]oxazolo[3,4-d]pyridazin-7-one
  • 2-(4-methoxyphenyl)-3,4-dimethyl-2,6-dihydro-7H-pyrazolo[3,4-d]pyridazin-7-one
  • 3,4-Dimethyl-6-phenylisoxazolo[3,4-d]pyridazin-7(6H)-one