L-NIL dihydrochloride

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Names

[ CAS No. ]:
159190-45-1

[ Name ]:
L-NIL dihydrochloride

[Synonym ]:
N(6)-acetimidoyl-L-lysine dihydrochloride
N-Ethanimidoyl-L-lysine dihydrochloride
l-n6-(1-iminoethyl)lysine dihydrochloride
L-Lysine, N-(1-iminoethyl)-, hydrochloride (1:2)

Chemical & Physical Properties

[ Boiling Point ]:
369ºC at 760 mmHg

[ Molecular Formula ]:
C8H19Cl2N3O2

[ Molecular Weight ]:
260.161

[ Flash Point ]:
177ºC

[ Exact Mass ]:
259.085419

[ PSA ]:
99.20000

[ LogP ]:
2.95030

[ Storage condition ]:
20°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S37/39

[ RIDADR ]:
NONH for all modes of transport

Articles

Effects of nitric oxide synthase deficiency on a disintegrin and metalloproteinase domain-containing protein 12 expression in mouse brain samples.

Mol. Med. Report. 12 , 2253-62, (2015)

A disintegrin and metalloproteinase domain-containing protein 12 (ADAM12) belongs to the ADAM family of transmembrane proteins. Via proteolysis, cell adhesion, cell-cell fusion, cell-matrix interactio...

Leptin administration activates irisin-induced myogenesis via nitric oxide-dependent mechanisms, but reduces its effect on subcutaneous fat browning in mice.

Int. J. Obes. 39(3) , 397-407, (2015)

BACKGROUND/OBJETIVES: Obese leptin-deficient ob/ob mice exhibit high adiposity and reduced muscle mass with leptin replacement promoting weight loss and inducing muscle accretion through PGC-1α-depend...

L-N6-(1-iminoethyl)lysine: a selective inhibitor of inducible nitric oxide synthase.

J. Med. Chem. 37 , 3886, (1994)

L-N6-(1-Iminoethyl)lysine (L-NIL) has been synthesized and is shown to be both a potent and selective inhibitor of mouse inducible nitric oxide synthase (miNOS). L-NIL has an IC50 of 3.3 microM for mi...


More Articles

Related Compounds

  • l-nil dihydrochloride
  • L-NIL
  • 1-Piperazineethanol, 4-(2-(3,4-dimethoxyphenyl)-1-(4-methylphenyl)ethy l)-, dihydrochloride
  • Benzofuro(3,2-c)pyridine, 1,2,3,4-tetrahydro-2-(3-(dimethylamino)propy l)-, dihydrochloride
  • 2-[4-[(4-propan-2-ylphenyl)-(thiazol-5-yl)methyl]piperazin-1-yl]ethano l dihydrochloride
  • Benzamide, 4-amino-N-(3-(tricyclo(3.3.1.1(sup 3,7))dec-1-ylamino)propy l)-, dihydrochloride
  • Tert-butyl 3-(2-bromoethynyl)-3-hydroxypyrrolidine-1-carboxylate
  • 6-chloro-N-[3-(1H-imidazol-1-yl)propyl]-4-methyl-1,3-benzothiazol-2-amine hydrate
  • 6-{4-[2-Hydroxy-2-(thiophen-2-yl)ethyl]piperazine-1-carbonyl}-2-methyl-2,3-dihydropyridazin-3-one hydrochloride
  • 1-[(5-Chloropyrimidin-2-yl)amino]-2-methyl-3-thiophen-3-ylpropan-2-ol
  • 3-methyl-2-{[1-(1-methyl-3-phenyl-1H-pyrazole-5-carbonyl)piperidin-4-yl]methoxy}pyridine
  • 3-Tert-butyl-6-{[1-(3-fluoro-4-methoxybenzenesulfonyl)piperidin-4-yl]methoxy}pyridazine
  • N-(2,6-difluorophenyl)-4-[3-(3,5-dimethyl-1H-pyrazol-1-yl)-6-oxo-1,6-dihydropyridazin-1-yl]piperidine-1-carboxamide
  • 5-Bromo-N-[1-(thiophen-3-ylmethyl)pyrrolidin-3-yl]thiophene-2-sulfonamide;hydrochloride
  • 1-(2,6-Difluorophenyl)-3-{[4-(furan-3-yl)thiophen-2-yl]methyl}urea
  • 1-(2,6-Difluorophenyl)-3-[(4-thiophen-3-ylthiophen-2-yl)methyl]urea
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