Everolimus (RAD001)
Suppliers
Names
[ CAS No. ]:
159351-69-6
[ Name ]:
Everolimus (RAD001)
[Synonym ]:
SDZRAD
Certican
Zortress
Afinitor
RAD-001
CERTICAN(R)
42-O-(2-Hydroxyethyl)-rapamycin
Everolimus
Certica
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
998.7±75.0 °C at 760 mmHg
[ Melting Point ]:
NA
[ Molecular Formula ]:
C53H83NO14
[ Molecular Weight ]:
958.224
[ Flash Point ]:
557.8±37.1 °C
[ Exact Mass ]:
957.581360
[ PSA ]:
204.66000
[ LogP ]:
3.35
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.548
[ Storage condition ]:
−20°C
[ Stability ]:
Hygroscopic
[ Water Solubility ]:
Soluble in dimethysulfoxide,ethanol and chloroform. Slightly soluble in water.
Safety Information
[ Symbol ]:
GHS02, GHS07
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H225-H302 + H332-H319
[ Precautionary Statements ]:
P210-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
[ Hazard Codes ]:
T
[ Risk Phrases ]:
R48/25
[ Safety Phrases ]:
S45
[ RIDADR ]:
UN 1648 3 / PGII
[ WGK Germany ]:
2
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
Antimicrob. Agents Chemother. 59(2) , 1088-99, (2015)
Middle East respiratory syndrome coronavirus (MERS-CoV) is a lineage C betacoronavirus, and infections with this virus can result in acute respiratory syndrome with renal failure. Globally, MERS-CoV h...
Clin. Biochem. 47(15) , 112-5, (2014)
Objectives Liquid chromatography tandem mass spectrometry has become increasingly popular in clinical laboratories over the last decade due to the inherent sensitivity and specificity of the technolog...
Ther. Drug Monit. 36(3) , 358-65, (2014)
Whole-blood concentrations of the immunosuppressant drugs everolimus and sirolimus should be monitored. A sensitive and selective method offering the detection of both analytes in small sample volumes...