4-Pyridylamidoxime

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Names

[ CAS No. ]:
1594-57-6

[ Name ]:
4-Pyridylamidoxime

[Synonym ]:
N-Hydroxyisonicotinamidine
MFCD00125873
Pyridine-4-carboxamide oxime
N-Hydroxy-4-pyridinecarboximidamide
N-Hydroxypyridine-4-carboximidamide
Isonicotinamide oxime
4-Pyridylamidoxime
T6NJ DYZUNQ
Isonicotinamidoxime
N'-hydroxypyridine-4-carboximidamide
T6NJ DYUM&MQ
4-Pyridinecarboximidamide, N'-hydroxy-
4-Pyridinecarboximidamide, N-hydroxy-
4-Pyridylamide oxime
N-Hydroxy-isonicotinamidine

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
350.0±34.0 °C at 760 mmHg

[ Melting Point ]:
128-133 °C(lit.)

[ Molecular Formula ]:
C6H7N3O

[ Molecular Weight ]:
137.139

[ Flash Point ]:
165.5±25.7 °C

[ Exact Mass ]:
137.058914

[ PSA ]:
71.50000

[ LogP ]:
-0.11

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.620

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NS1050000
CHEMICAL NAME :
Isonicotinamidoxime
CAS REGISTRY NUMBER :
1594-57-6
LAST UPDATED :
198609
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C6-H7-N3-O
MOLECULAR WEIGHT :
137.16

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
321 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
REFERENCE :
AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.10- 1962- Volume(issue)/page/year: 25,839,1977

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
NS1050000

[ HS Code ]:
2933399090

Synthetic Route

Precursor & DownStream

Precursor

  • Isonicotinonitrile
  • Hydroxyamine hydrochloride
  • Isonicotinic acid

DownStream

  • 4-[5-(Chloromethyl)-1,2,4-Oxadiazol-3-Yl]Pyridine
  • 6-methyl-1-oxido-2-pyridin-4-ylpyrimidin-1-ium
  • 4-Pyridinecarboximidamide hydrochloride
  • 3-pyridin-4-yl-2H-1,2,4-oxadiazole-5-thione
  • [3-(4-pyridinyl)-1,2,4-oxadiazol-5-yl]methanol(SALTDATA: FREE)
  • 5-(4-methylphenyl)-3-pyridin-4-yl-1,2,4-oxadiazole
  • 5-(3-methylphenyl)-3-pyridin-4-yl-1,2,4-oxadiazole

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

A 'one-pot'synthesis of a-1, 2, 4-oxadiazolo esters from malonic diesters and amidoximes under solvent-free conditions. Du W, et al.

Tetrahedron Lett. 47(25) , 4271-4274, (2006)


More Articles


Related Compounds

  • 4-PyridylamidoxiMe
  • 4-Amino-2-chloro-5-(1H-tetrazol-5-yl)benzenesulfonamide
  • 4-(4-Chlorophenyl)-4-Bromopiperide
  • 4-(2-nitroimidazol-1-yl)butane-1,2-diol
  • 4-Iodo-1H-indazole-3-carboxylic acid
  • 4-chlorooxolan-3-ol,formic acid
  • 4-chloro-N-(4-ethyl-5-oxo-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepin-7-yl)benzenesulfonamide
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • N-(4-(4-methoxyphenyl)-5-methylthiazol-2-yl)-1,3-dimethyl-1H-pyrazole-5-carboxamide
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • N-(2H-1,3-benzodioxol-5-yl)-1-({4-oxo-5-phenyl-3H,4H-thieno[2,3-d]pyrimidin-2-yl}methyl)piperidine-4-carboxamide
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 1-(5-Chloro-2-methylphenyl)-1H-tetrazole-5-thiol